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The ageLOC TRMe & R² 90-Day Kit combines the full TRMe weight management system with R²'s day-and-night cellular energy protocol over 90 days at US$1,446.15. This is Nu Skin's most comprehensive weight management bundle — six products addressing appetite (Slim-S), metabolic rate (SmartWin), emotional cravings (MyTriumph), protein nutrition (Protein), daytime cellular energy (R² Day), and overnight cellular purification (R² Night). The rationale is clear: weight management programs are demanding on your body's energy systems, and R² supports cellular energy production and waste clearing during the process.
When you're running a calorie deficit, your body needs to produce energy more efficiently from less fuel. R² Day supports that mitochondrial efficiency through Cordyceps Cs-4 and pomegranate extract. R² Night supports the increased cellular waste processing that comes with fat metabolism — when your body breaks down stored fat, it generates metabolic byproducts that need to be cleared. Milk thistle and broccoli seed extract in R² Night support the detoxification pathways responsible for this clearance.
This is the most capsule-intensive program in the range — roughly 12-14 capsules daily plus a protein shake. It requires genuine commitment and organizational effort. Most customers investing at this level are already experienced with Nu Skin supplements and are stepping up to a comprehensive protocol.
TRMe system: Bupleurum root, EGCG + capsicum + guarana, saffron + L-theanine, plant protein (15g/serve).
R² Day: Cordyceps Cs-4, pomegranate extract, chokeberry — daytime cellular energy support.
R² Night: Milk thistle, broccoli seed extract, curcumin — overnight cellular purification.
Morning: R² Day (2 capsules) + SmartWin (1) + MyTriumph (1) with breakfast. Slim-S (2) before breakfast. Midday: Slim-S (2) before lunch, SmartWin (1) + MyTriumph (1) with lunch. Protein shake replaces one meal. Evening: Slim-S (2) before dinner. Bedtime: R² Night (2 capsules). Organize capsules into morning, midday, evening, and bedtime groups for manageable daily compliance.
Ideal for: Committed users who want maximum support during a 90-day weight management effort — addressing appetite, metabolism, mood, nutrition, energy, and cellular detoxification simultaneously.
Not recommended for: First-time supplement users or anyone not ready for a multi-product daily protocol. Start with the standard TRMe 30-day kit to determine if the structured approach works for your lifestyle.
Can I buy this in the US without signing up?
Yes. No membership needed. Ships from the official US warehouse.
Is R² necessary during TRMe?
Optional. TRMe works as a complete standalone system. R² adds cellular energy and purification support that some users find helpful during the metabolic demands of weight management, particularly if exercising regularly.
How many capsules per day?
Approximately 12-14 capsules/sachets daily plus the protein shake. Organize into morning, midday, evening, and bedtime groups.
FDA Notice: *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Consult your healthcare provider before beginning any weight management program. Contains caffeine (SmartWin). Keep out of reach of children.
Affiliate Disclosure: NuBest Skin is an Independent Nu Skin Brand Affiliate. This website is independently operated and is not produced, endorsed, supported, or affiliated with Nu Skin Enterprises, Inc.
Reviewed by the NuBest Skin Editorial Team. Last updated: April 2026.
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