ageLOC TRMe® 90-Day Kit with Nu Biome®

This bundle combines the full 90-day TRMe weight management system with Nu Biome gut health support at US$1,369.23. The rationale is sound: gut microbiome composition directly influences metabolic function, appetite signaling, and how efficiently your body processes nutrients during a calorie-restricted program. Adding Nu Biome's postbiotic and prebiotic formula to TRMe's multi-product weight management protocol addresses the gut-metabolic axis alongside appetite, metabolism, mood, and protein intake.

What Makes This Bundle Different

The gut-metabolic connection is well-established in clinical research. A 2019 review in Nature Reviews Endocrinology (PMID: 30670819) documented how specific microbial metabolites directly regulate host metabolic pathways. During a weight management program like TRMe, your gut microbiome composition shifts in response to dietary changes — Nu Biome's prebiotic fibers (FOS and XOS) support beneficial bacteria populations during this transition, while the postbiotic compounds support gut barrier integrity and metabolic signaling.

This bundle includes everything in the standard 90-day TRMe kit (Slim-S, SmartWin, MyTriumph, Protein) plus 90 days of Nu Biome. It's the most gut-inclusive weight management option in Nu Skin's range.

Key Ingredients

TRMe system: Bupleurum root (appetite), EGCG + capsicum (metabolism), saffron + L-theanine (mood/cravings), plant protein (15g/serve).

Nu Biome: Postbiotic metabolites + FOS + XOS prebiotic fibers for gut-metabolic axis support.

How to Use

Follow the standard TRMe daily protocol (Slim-S before meals, SmartWin + MyTriumph with breakfast/lunch, Protein shake replacing one meal). Add one Nu Biome stick pack mixed in water daily — morning or evening. The prebiotic fibers may cause mild bloating in the first few days as your gut adjusts; this typically resolves within 3-5 days.

Who Is This For

Ideal for: Anyone committing to the 90-day TRMe program who also wants gut health optimization during the weight management process. Especially relevant if you've experienced digestive changes during previous diets or weight management attempts.

Not recommended for: First-time TRMe users — start with the 30-day kit to confirm the protocol works for you before adding Nu Biome to a 90-day commitment.

Frequently Asked Questions

Can I buy this in the US without signing up?
Yes. No membership needed. Ships from the official US warehouse.

Is Nu Biome essential for TRMe to work?
No. TRMe works as a standalone system. Nu Biome adds gut-metabolic support that may enhance results, particularly for people who experience digestive issues during dietary changes.

Important Information

FDA Notice: *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Consult your healthcare provider before beginning any weight management program. Contains caffeine (SmartWin). Keep out of reach of children.

Affiliate Disclosure: NuBest Skin is an Independent Nu Skin Brand Affiliate. This website is independently operated and is not produced, endorsed, supported, or affiliated with Nu Skin Enterprises, Inc.

Sources & References

1. Fan Y, Pedersen O. "Gut microbiota in metabolic health." Nature Reviews Endocrinology, 2019. PMID: 30670819.
2. Nu Skin Enterprises, Inc. — TRMe and Nu Biome product documentation.

Reviewed by the NuBest Skin Editorial Team. Last updated: April 2026.