Cordyceps CS-4 (AU)

Cordyceps CS-4 is Nu Skin's standardised Cordyceps sinensis extract, using the Cs-4 strain that's been the focus of most clinical research on this adaptogenic fungus. It supports cellular energy production through ATP (adenosine triphosphate) pathways and helps the body utilise oxygen more efficiently during physical activity. If you're looking for a natural way to support stamina and endurance without stimulants, Cordyceps Cs-4 is one of the better-researched options available in Australia.

What Makes It Different

Wild Cordyceps sinensis is prohibitively expensive — it can sell for AU$20,000+ per kilogram in Asian markets because it's harvested from caterpillar hosts at high altitude in the Tibetan plateau. Most "Cordyceps" supplements use Cordyceps militaris (a different species) or non-standardised mycelium. Nu Skin's Cordyceps CS-4 uses the Cs-4 strain of Cordyceps sinensis, which was developed through fermentation to replicate the bioactive profile of wild Cordyceps at a fraction of the cost.

The Cs-4 strain is specifically the one used in the clinical trial by Chen S, et al. published in the Journal of Alternative and Complementary Medicine (2010;16(5):585-590), which demonstrated improved exercise performance in healthy older adults after 12 weeks of supplementation. Participants showed measurable improvements in maximal oxygen consumption (VO2 max) and ventilatory threshold. This is the strain you want if you're basing your decision on published evidence rather than marketing claims.

Key Ingredients

Cordyceps sinensis Cs-4 Extract: The Cs-4 strain is produced through controlled fermentation that yields a consistent adenosine content — one of the primary active compounds. Adenosine plays a direct role in ATP energy production at the mitochondrial level. The Cs-4 fermentation process produces a mycelial biomass with a bioactive profile closely matching wild Cordyceps, which has been validated through HPLC analysis.

Cordycepin: A nucleoside analogue unique to Cordyceps species. Cordycepin (3'-deoxyadenosine) supports cellular energy metabolism and has been studied for its effects on oxygen utilisation efficiency. It's structurally similar to adenosine but with distinct biological activity. The Cs-4 strain produces measurable cordycepin levels, unlike some cheaper Cordyceps militaris extracts that prioritise growth speed over compound density.

Polysaccharides: Cordyceps polysaccharides support immune function through beta-glucan receptor activation on immune cells. They also contribute to the adaptogenic properties of the extract — helping the body manage physical stress more effectively. The standardised extract ensures consistent polysaccharide content across production batches, which isn't guaranteed in non-standardised Cordyceps products.

How Australians Are Using It

Take 2 capsules twice daily with food. Athletes and regular gym-goers often take their morning dose 60–90 minutes before training for the ATP support benefits. Unlike caffeine-based pre-workouts, Cordyceps doesn't cause a crash or interfere with sleep if taken later in the day. It's particularly popular among endurance athletes — trail runners and cyclists in Australia's Blue Mountains, Victorian Alps, and coastal routes — who want sustained energy without stimulant dependency.

Who Is This For

Cordyceps CS-4 is a good fit for active Australians who want to support their energy levels and exercise capacity naturally. It's also used by people in their 40s–60s who've noticed declining stamina and want to support mitochondrial function. It won't replace proper training, sleep, or nutrition — but the published research suggests it can provide a meaningful edge when those fundamentals are already in place.

FAQ

Can I buy Cordyceps CS-4 in Australia without signing up?
Yes. NuBest Skin sells Cordyceps CS-4 with no Nu Skin membership, subscription, or auto-ship required. Order online and it ships from the official Australian warehouse.

How long does it take to notice an effect?
The Chen et al. (2010) study showed measurable improvements after 12 weeks. Most users report subjective improvements in energy and exercise tolerance within 3–6 weeks, but cellular-level ATP support isn't something you'll feel after a single dose. Give it at least a month of consistent use.

Is this the same as wild Cordyceps?
Not exactly. Wild Cordyceps sinensis grows on caterpillar larvae at 3,000–5,000m altitude and costs thousands per kilogram. The Cs-4 strain is a fermented equivalent that replicates the bioactive profile of wild Cordyceps — same species, same key compounds, but produced sustainably and affordably through controlled fermentation. HPLC analysis shows comparable adenosine and polysaccharide profiles.

Important Information

Always read the label and follow the directions for use. Supplements should not replace a balanced diet. If symptoms persist, consult your healthcare professional. Not suitable for children under 15 years unless advised by a healthcare practitioner. If you are pregnant, breastfeeding, or taking prescription medication, consult your doctor before use.

This information is provided for educational purposes only and does not constitute medical advice. Individual results may vary.

NuBest Skin is an Independent Nu Skin Brand Affiliate. This website is independently operated and is not produced, endorsed, or approved by Nu Skin Enterprises, Inc.

Product information reviewed by the NuBest Skin Editorial Team. Last updated April 2026.