ageLOC® Y-Span® & ageLOC® R² Kit (AU)

The ageLOC Y-Span & R² Kit is Nu Skin's most comprehensive anti-ageing supplement bundle for Australia — Y-Span for broad-spectrum vitality across six gene cluster pathways, plus the R² day-and-night cellular system for targeted energy production and overnight detoxification. Bundled at AU$335, it saves around AU$9 versus buying Y-Span (AU$189) and R² (AU$155) separately. The dollar saving is modest; the real value is that the two products are formulated to complement each other without ingredient redundancy.

What's Included

• ageLOC Y-Span — broad-spectrum anti-ageing formula targeting Youth Gene Clusters across six pathways (cardiovascular, brain, immune, metabolism, cellular defence, DNA repair). Hero actives include alpha-lipoic acid, astaxanthin, CoQ10, resveratrol, and vitamin D3. 30-day supply (typically 2 capsules twice daily with meals).
• ageLOC R² Day — daytime cellular energy capsules. Cordyceps sinensis Cs-4, pomegranate extract, and chokeberry extract for mitochondrial ATP production. 30-day supply.
• ageLOC R² Night — overnight cellular purification capsules. Milk thistle (silymarin), broccoli seed extract (sulforaphane precursor), and curcumin for liver phase II detoxification and Nrf2 antioxidant pathway support. 30-day supply.

Why This Bundle

Y-Span and R² are designed to address different layers of the ageing problem. Y-Span operates at the macro level — a single formula influencing gene expression patterns across six broad pathways. R² operates at the cellular performance layer — a two-formula system that aligns mitochondrial energy support to the active hours and liver detoxification support to the overnight repair window. There's no meaningful ingredient overlap between them; each product covers what the other doesn't.

Used together, the two products give you broad-spectrum gene expression maintenance (Y-Span) plus circadian-aligned cellular performance (R²) — which is the most complete ageLOC anti-ageing protocol Nu Skin currently offers. The kit is the obvious purchase if you've already decided you want to run both. If you're new to both products, the R² combined box alone is a reasonable starting point because the day-night energy and detox effects are more immediately noticeable, then add Y-Span once R² is established in the routine.

vs Buying Separately

Who It's For

✅ Best suited for: Adults over 35 who want the most comprehensive ageLOC anti-ageing protocol available — broad gene-expression coverage plus targeted day/night cellular performance. Particularly suited to customers who've already used either Y-Span or R² individually and want to add the other.

⚠️ Less suited for: First-time supplement users — start with one product first to assess tolerance and benefit before committing to the full kit. Anyone with patchy nutritional foundations should consider LifePak first; Y-Span and R² assume basic micronutrient intake is in order.

💡 Pairs well with: LifePak as the nutritional foundation underneath this anti-ageing layer, or ageLOC Meta for additional metabolic and gut metabolome support.

How Australians Are Using This Kit

This kit is typically purchased by committed Nu Skin supplement users — often people who've already tried R² or Y-Span individually and want the full anti-ageing protocol. The daily routine is straightforward: Y-Span (2 capsules) plus R² Day (1–2 capsules) with breakfast, then Y-Span (2 capsules) and R² Night (1–2 capsules) with the evening meal. Take with food — the formulas contain fat-soluble actives that absorb significantly better with dietary fat present.

It's a considered investment at AU$335 per 30-day cycle that appeals to customers who are serious about proactive ageing support, usually in the 40+ bracket. Most users notice sustained-energy changes within 2–3 weeks (driven mainly by R² Day); the broader Y-Span benefits — sleep quality, recovery, biomarker shifts — typically show up around the 4–6 week mark and continue developing over 3–6 months.

Frequently Asked Questions

What's included in this kit?
Three products: ageLOC Y-Span (broad-spectrum anti-ageing formula), R² Day (daytime cellular energy capsules), and R² Night (overnight cellular purification capsules). All three together cover a 30-day supply.

Is the kit cheaper than buying separately?
Yes — modestly. The kit is AU$335. Buying Y-Span (AU$189) and the R² combined box (AU$155) separately totals AU$344, so the kit saves around AU$9 per cycle. If you bought the R² standalone Day and Night units instead of the combined box, the standalone path totals AU$364.99 and the kit saves around AU$30.

Is this the most comprehensive ageLOC anti-ageing combo available?
Yes. Y-Span covers broad gene-expression maintenance across six pathways, and R² covers targeted day/night cellular performance. Together they're the most complete ageLOC anti-ageing protocol Nu Skin currently offers.

Can I add LifePak to this routine?
Yes, and it makes sense to. LifePak covers comprehensive micronutrient intake (58+ nutrients, omega-3s, chelated minerals). Y-Span and R² assume that nutritional foundation is in place — adding LifePak underneath gives you the full nutritional substrate plus the anti-ageing performance layer on top. Some overlap on vitamin D3 and CoQ10, but combined intake remains within safe upper limits for healthy adults.

How many capsules per day is this in total?
Eight capsules daily across two doses: Y-Span (2 caps) + R² Day (2 caps) with breakfast, then Y-Span (2 caps) + R² Night (2 caps) with the evening meal. Standard-sized capsules, easy to take with meals.

Important Information

Always read the label and follow the directions for use. Supplements should not replace a balanced diet. If symptoms persist, consult your healthcare professional. Not suitable for children under 15 years unless advised by a healthcare practitioner. If you are pregnant, breastfeeding, or taking prescription medication (particularly anticoagulants, immunosuppressants, or drugs metabolised through cytochrome P450 pathways given the silymarin content), consult your doctor before use. This information is provided for educational purposes only and does not constitute medical advice. Individual results may vary.

NuBest Skin is an Independent Nu Skin Brand Affiliate. This website is independently operated and is not produced, endorsed, or approved by Nu Skin Enterprises, Inc.

Sources & References

• Nu Skin Enterprises — official ageLOC Y-Span and ageLOC R² product specifications.
• Therapeutic Goods Administration (Australia) — listed medicine guidelines for complementary medicines, tga.gov.au.
• Australian Bureau of Statistics — Australian Health Survey: Biomedical Results for Nutrients, 2011–12.
• Product information reviewed by the NuBest Skin Editorial Team. Last updated April 2026.