ageLOC® Y-Span® & ageLOC® R² Kit (AU)

The ageLOC Y-Span & R² Kit is Nu Skin's most comprehensive anti-ageing supplement bundle for Australia. Y-Span targets the body's youth gene clusters — groups of genes associated with ageing — while R² provides a day-and-night cellular energy and purification system. Together, they address ageing from two complementary angles: broad gene expression support and targeted cellular vitality. At AU$335, the saving versus buying Y-Span (AU$189) and R² (AU$155) separately is modest at ~AU$9, but the real value is in the complementary formulation.

What's Included

• ageLOC Y-Span — targets Youth Gene Clusters (YGCs) identified through Nu Skin's gene expression research. Contains a proprietary blend of ingredients including pomegranate extract, red orange complex, and cordyceps designed to support youthful gene expression patterns across multiple body systems. 120 capsules (30-day supply, 4 daily).
• ageLOC R² — a two-part system with daytime (R² Day) and night-time (R² Night) capsules. Day formula includes Cordyceps Cs-4 and pomegranate for cellular energy production. Night formula contains milk thistle, broccoli seed extract, and curcumin for overnight cellular purification. 30-day supply (2 Day + 2 Night capsules daily).

How They Work Together

Y-Span works broadly across the body's gene expression landscape — Nu Skin's research identified clusters of genes whose expression patterns change with age, and Y-Span's formula is designed to support more youthful expression patterns across these clusters. R² then addresses a specific aspect of cellular health: energy production during the day (via mitochondrial support) and detoxification at night (via antioxidant and liver-support compounds).

The combination makes sense because gene expression and cellular energy are interconnected. Cells that produce energy more efficiently and clear waste products more effectively are better positioned to maintain youthful function. You're essentially supporting the macro level (gene expression) and micro level (individual cell energy) simultaneously.

How Australians Are Using This Kit

This is typically purchased by committed Nu Skin supplement users — often people who've already tried R² or Y-Span individually and want the full anti-ageing protocol. The daily routine involves 4 Y-Span capsules and 2 R² Day capsules with breakfast, then 2 R² Night capsules before bed. It's not a casual starter kit; at AU$335 per month, it's a considered investment that appeals to customers who are serious about proactive ageing support, usually in the 45–65 age bracket.

Frequently Asked Questions

Can I buy this kit in Australia without signing up?
Yes. No membership or registration required at NuBest Skin. Order directly from our website and your kit ships from the official Nu Skin warehouse in Australia.

Is this worth the premium over buying just R² or Y-Span alone?
The AU$9 kit saving is small, but the real question is whether you want both products. If you're already taking one and considering adding the other, the kit is the logical way to buy them. If you're new to both, starting with R² alone is a reasonable first step — it's more immediately noticeable in terms of daily energy.

How many capsules per day is this in total?
Eight capsules daily: 4 Y-Span + 2 R² Day in the morning, 2 R² Night in the evening. It's a commitment, but the capsules are standard-sized and easy to take with meals.

Important Information

Always read the label and follow the directions for use. Supplements should not replace a balanced diet. If symptoms persist, consult your healthcare professional. Not suitable for children under 15 years unless advised by a healthcare practitioner. If you are pregnant, breastfeeding, or taking prescription medication, consult your doctor before use.

This information is provided for educational purposes only and does not constitute medical advice. Individual results may vary.

NuBest Skin is an Independent Nu Skin Brand Affiliate. This website is independently operated and is not produced, endorsed, or approved by Nu Skin Enterprises, Inc.

Product information reviewed by the NuBest Skin Editorial Team. Last updated April 2026.