Probio Pcc™ (AU)

Probio PCC is Nu Skin's targeted probiotic supplement containing Lactobacillus reuteri NCIMB 30242, a specific bacterial strain studied for its role in cardiovascular health and cholesterol management. Unlike general digestive probiotics that use common Lactobacillus acidophilus or Bifidobacterium strains, Probio PCC uses a strain with published clinical evidence for supporting healthy cholesterol levels. It also provides general digestive and gut health benefits, but the cardiovascular angle is what sets it apart from the crowded probiotic market in Australia.

What Makes It Different

Most probiotics in Australia are formulated for digestive health — bloating, regularity, general gut flora support. Probio PCC targets a different mechanism entirely. The L. reuteri NCIMB 30242 strain has been shown in a randomised, double-blind, placebo-controlled trial by Jones ML, et al. (European Journal of Clinical Nutrition, 2012;66(11):1234-1241) to reduce LDL cholesterol by 11.64% over 9 weeks compared to placebo. It works by deconjugating bile salts in the gut, which increases bile acid excretion and forces the liver to pull more cholesterol from the bloodstream to make new bile acids.

That's a specific, well-understood mechanism — not a vague "supports gut health" claim. The strain specificity matters enormously in probiotics: you can't swap in a different Lactobacillus strain and expect the same cholesterol-related results. NCIMB 30242 is the exact strain used in the published research, and that's the strain in Probio PCC. Many probiotic products don't even identify their strains at the sub-species level, which makes it impossible to verify their claims against published studies.

Key Ingredients

Lactobacillus reuteri NCIMB 30242: This specific strain produces bile salt hydrolase (BSH), an enzyme that deconjugates bile acids in the small intestine. Deconjugated bile acids are less efficiently reabsorbed, which increases their excretion. The liver compensates by converting more circulating cholesterol into bile acids — effectively pulling LDL cholesterol out of the bloodstream. The Jones et al. (2012) trial demonstrated an 11.64% reduction in LDL-C and a 9.14% reduction in total cholesterol over 9 weeks at the studied dose.

Probiotic Colony Forming Units (CFUs): Probio PCC delivers a clinically relevant CFU count that matches the dose used in published studies. CFU count at the time of manufacture vs. at the time of consumption can differ significantly — heat, moisture, and time all reduce viable bacteria. Nu Skin's encapsulation technology is designed to maintain viable CFU counts through the shelf life, not just at the time of production. This is a distinction worth checking on any probiotic label.

Targeted Delivery Format: The capsule format is designed to survive stomach acid and deliver viable bacteria to the small intestine where bile salt metabolism occurs. Probiotics that die in stomach acid before reaching the intestine can't deliver their intended benefits — regardless of how many CFUs were on the label. The acid-resistant capsule is essential for this particular mechanism of action.

How Australians Are Using It

Take the recommended daily dose with a meal. Probiotics generally do better when taken with food — the meal buffers stomach acid and provides nutrients for the bacteria. Store in a cool, dry place; while Probio PCC is shelf-stable, excessive heat (above 30°C) will reduce viable bacteria over time. In Australian summers, particularly in northern states, it's worth keeping them away from direct sunlight or hot cars. Consistency is important — the cholesterol-related benefits in the Jones et al. study were observed after 9 weeks of daily use.

Who Is This For

Probio PCC is specifically suited for adults concerned about cholesterol management who want a natural approach alongside diet and lifestyle changes. It's not a replacement for statins or other prescribed cholesterol medication — if your doctor has prescribed medication, don't stop taking it in favour of a probiotic. But for people in the early stages of cholesterol concern, or those already managing their levels through diet and exercise, Probio PCC adds a clinically studied mechanism that most probiotic products simply don't offer.

FAQ

Can I buy Probio PCC in Australia without signing up?
Yes. NuBest Skin sells Probio PCC directly with no Nu Skin membership, auto-ship, or registration. Order online and it ships from the official Australian warehouse.

Does it help with general digestive health too?
Yes — L. reuteri is a natural inhabitant of the human gut and supports general digestive balance. However, if your primary goal is digestive comfort (bloating, irregularity), a broader-spectrum probiotic with multiple strains might be more appropriate. Probio PCC's standout feature is the cholesterol mechanism, with digestive support as a secondary benefit.

Can I take it with other medications?
If you're taking cholesterol-lowering medication (statins, fibrates, etc.), consult your doctor before adding Probio PCC. There's no known harmful interaction, but your doctor should be aware of anything that may affect your cholesterol levels so they can monitor appropriately. For other medications, the general advice is to take probiotics at least 2 hours apart from antibiotics.

Important Information

Always read the label and follow the directions for use. Supplements should not replace a balanced diet. If symptoms persist, consult your healthcare professional. Not suitable for children under 15 years unless advised by a healthcare practitioner. If you are pregnant, breastfeeding, or taking prescription medication, consult your doctor before use.

This information is provided for educational purposes only and does not constitute medical advice. Individual results may vary.

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Product information reviewed by the NuBest Skin Editorial Team. Last updated April 2026.