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TRME MyEDGE is the fat management component of Nu Skin's TRME weight management system, delivering CLA (conjugated linoleic acid) at a clinically studied dose alongside gene expression targeting. A 2007 meta-analysis in the American Journal of Clinical Nutrition, analysing 18 trials, found that CLA at approximately 3.2 g/day produced consistent reductions in body fat mass — modest but reliable when sustained over 6+ months. MyEDGE targets how your body stores and processes dietary fat, complementing REALMe (appetite) and MyGOAL (metabolism) in the three-pillar TRME system.
CLA supplements are available at Dis-Chem from brands like USN and Weider. MyEDGE's differentiation is the gene expression component — targeting Youth Gene Clusters associated with fat metabolism that become less efficient with age. CLA works through direct biochemical pathways (inhibiting fat storage, promoting fat oxidation); the gene expression blend addresses the age-related genetic changes that make fat increasingly stubborn.
CLA (Conjugated Linoleic Acid): Naturally occurring fatty acid. Meta-analysis of 18 trials showed average fat loss of 0.09 kg/week. Works through multiple mechanisms: inhibiting adipocyte fat storage, promoting fat oxidation, supporting lean mass retention.
Gene Expression Blend: Targets fat metabolism Youth Gene Clusters that downregulate with age.
Take 3 softgels twice daily with meals (6 total/day). Split between breakfast and dinner. CLA absorbs better with dietary fat. Results are gradual — expect 6–12 weeks for measurable body composition changes. Pair with regular activity for best results.
| Feature | TRME MyEDGE | USN CLA Green Tea | Weider CLA |
|---|---|---|---|
| CLA Dose/Day | Clinical dose | ~3,000 mg | ~1,500 mg |
| Gene Expression | Yes | No | No |
| Part of System | Yes (TRME trio) | Standalone | Standalone |
| SA Brand | No | Yes (USN) | No (international) |
| Price | R1,199/month | ~R300/month | ~R250/month |
USN's CLA delivers good value from a trusted SA brand. MyEDGE adds gene expression targeting and system integration with REALMe and MyGOAL. For standalone CLA, USN is solid. For the full TRME system approach, MyEDGE is the third pillar.
If stubborn body fat — particularly around the midsection — isn't responding to diet and exercise the way it used to, age-related changes in fat metabolism gene expression may be contributing. MyEDGE addresses this specifically.
If you're using the full TRME system, MyEDGE completes the trio: REALMe (appetite) + MyGOAL (metabolism) + MyEDGE (fat management).
Not suitable for under-18s, pregnant/nursing women, or those with liver conditions. Mild GI adjustment in the first week is normal.
Q: How do I buy MyEDGE in South Africa?
Order from nubestskin.com. Standard shipping: R99, free over R1,999. Delivery: 3–7 business days.
Q: Can I just buy regular CLA?
Yes — USN or Weider CLA provides the base ingredient at lower cost. MyEDGE adds gene expression targeting. If budget matters most, standalone CLA works. If you want the age-related fat metabolism component, MyEDGE is unique.
Q: How long before body composition changes?
8–12 weeks for measurable results. Body composition changes (more definition, less softness) appear before scale changes.
Q: Are there side effects?
Mild digestive adjustment in week 1 is possible. Taking with meals minimises this. Resolves within days.
TRME REALMe: Reduces calorie intake via appetite management.
TRME MyGOAL: Increases calorie expenditure via thermogenesis.
TRME M-Bars: Convenient protein-rich snack supporting lean mass during weight management.
Important Information: This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare professional before use, especially if you are pregnant, nursing, taking medication, or have a medical condition. Complementary medicines are regulated by SAHPRA. Individual results may vary. Store in a cool, dry place.
NuBest Skin is an Independent Nu Skin Brand Affiliate. This content is not produced or endorsed by Nu Skin Enterprises Inc.
Whigham, L. D., et al. (2007). Efficacy of CLA for reducing fat mass. American Journal of Clinical Nutrition, 85(5), 1203–1211.
Reviewed by the NuBest Skin Editorial Team. Last updated: April 2026.
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