Estera® Phase II Women's Transitions Formula (USA)

Estera Phase II is a women's health supplement designed for the perimenopausal and menopausal transition — the period when estrogen levels fluctuate and decline, causing symptoms like hot flashes, night sweats, mood changes, and sleep disruption. At US$64.00 for a 30-day supply, it uses soy isoflavones and black cohosh, two of the most-studied natural alternatives to hormone replacement therapy (HRT) for managing menopausal symptoms. For the approximately 6,000 American women who reach menopause daily, managing the transition naturally is a significant concern.

What Makes Estera Phase II Different

The "Phase II" designation indicates this formula is specifically for women in active transition — experiencing perimenopause or early menopause symptoms. Soy isoflavones are phytoestrogens that bind weakly to estrogen receptors, providing mild estrogenic activity that helps buffer the hormonal fluctuations causing symptoms. A meta-analysis in Menopause (2012, PMID: 22713856) confirmed that soy isoflavones reduce hot flash frequency by approximately 21% compared to placebo. Black cohosh has been studied in over 30 clinical trials for menopause symptom relief.

Key Ingredients

Soy isoflavones (genistein, daidzein) — phytoestrogens that provide mild estrogenic activity, helping buffer hormonal fluctuations during menopause.

Black cohosh (Cimicifuga racemosa) — traditional botanical for menopause symptoms with extensive clinical evidence for hot flash reduction.

How to Use

Take daily with food. Phytoestrogens and black cohosh require consistent daily use for 4-8 weeks before meaningful symptom reduction. This isn't a quick fix for an acute hot flash — it's daily support that moderates the frequency and severity of symptoms over time.

Who Is This For

Ideal for: Women in perimenopause or early menopause experiencing hot flashes, night sweats, or mood fluctuations who want natural symptom management without HRT.

Also suited for: Women who've tried HRT but experienced side effects and want a botanical alternative.

Not recommended for: Women with estrogen-sensitive conditions (certain breast cancers, endometriosis) — consult your oncologist or gynecologist before using phytoestrogens.

Frequently Asked Questions

Can I buy this without signing up?
Yes. No membership needed. Ships from the official US warehouse.

What's the difference between Phase II and Phase III?
Phase II is for active transition (perimenopause/early menopause). Phase III is the maintenance formula for post-menopausal women who've completed the transition and want ongoing support.

Important Information

FDA Notice: *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Consult your healthcare provider before use if you are pregnant, nursing, taking medication, or have a medical condition. Keep out of reach of children.

Affiliate Disclosure: NuBest Skin is an Independent Nu Skin Brand Affiliate. This website is independently operated and is not produced, endorsed, supported, or affiliated with Nu Skin Enterprises, Inc.

Sources & References

1. Taku K, et al. "Soy isoflavones for menopausal hot flashes." Menopause, 2012. PMID: 22713856.
2. Nu Skin Enterprises, Inc. — Estera Phase II documentation.

Reviewed by the NuBest Skin Editorial Team. Last updated: April 2026.