LifePak® Anti-Aging Formula (USA)

LifePak is Nu Skin's comprehensive daily multivitamin — a twice-daily packet delivering over 60 antioxidants, vitamins, and minerals in clinically relevant doses. At US$82.00 for a 30-day supply, it costs more than a Centrum or One A Day from the CVS shelf, but it's formulated to a different standard: bioavailable forms of each nutrient, doses based on clinical research rather than minimum RDA values, and a broad antioxidant complex that most drugstore multivitamins simply don't include. If you've been taking a basic multivitamin "just in case" without much thought, LifePak is what the upgrade looks like.

What Makes LifePak Different

The American multivitamin market is enormous and mostly mediocre. Centrum Silver, the best-selling multivitamin in the US, uses cheap nutrient forms — oxide-based minerals with poor absorption, synthetic vitamin E (dl-alpha), and minimal antioxidant coverage. Ritual Essential, the buzzy DTC brand, includes only 10 nutrients at meaningful doses and skips antioxidants entirely by design. LifePak takes the opposite approach: comprehensive coverage with over 60 ingredients, using forms your body can actually absorb.

For example, LifePak uses chelated minerals (bound to amino acids for better intestinal absorption) rather than the oxide forms found in most drugstore vitamins. Magnesium oxide, the cheapest form used in budget multivitamins, has roughly 4% bioavailability — meaning 96% of what you swallow passes through unabsorbed. Chelated magnesium absorbs at rates closer to 40-60%. The same principle applies across the mineral profile: zinc, chromium, selenium, and copper are all delivered in chelated or otherwise bioavailable forms.

The antioxidant complex is the other major differentiator. LifePak contains alpha-lipoic acid, grape seed extract, green tea catechins, lycopene, and lutein — a broad-spectrum antioxidant profile that covers different cellular compartments (water-soluble and fat-soluble environments). Most competing multivitamins either skip antioxidants or include token amounts. AG1, which has become the trendy "daily greens" in the US market, includes some antioxidant coverage but at undisclosed doses (it's a proprietary blend) and lacks the mineral comprehensiveness of LifePak.

Key Ingredients

Chelated minerals (calcium, magnesium, zinc, chromium, selenium) — amino acid-chelated forms provide significantly better absorption than oxide or carbonate forms. A study in the Journal of the American College of Nutrition (2014) demonstrated 2-4x higher bioavailability for chelated minerals compared to non-chelated equivalents.

Mixed tocopherols (vitamin E complex) — includes alpha, beta, gamma, and delta tocopherols, not just synthetic dl-alpha-tocopherol. Research published in the American Journal of Clinical Nutrition (2012, PMID: 22338079) shows that gamma-tocopherol has anti-inflammatory properties that alpha-tocopherol alone doesn't provide.

Alpha-lipoic acid (ALA) — one of the few antioxidants that functions in both water-soluble and fat-soluble cellular environments. It also regenerates other antioxidants (vitamins C and E, glutathione), effectively extending their activity. Doses in LifePak exceed what most multivitamins include.

Grape seed extract (OPCs) — oligomeric proanthocyanidins provide potent vascular and skin-supportive antioxidant effects. A meta-analysis in Nutrition Reviews (2020, PMID: 31504781) confirmed systolic blood pressure reduction and improved endothelial function with daily grape seed extract supplementation.

Full B-complex at therapeutic doses — B1, B2, B3, B5, B6, B12, folate, and biotin at doses well above RDA but within safe upper limits. These support energy metabolism, nervous system function, and homocysteine regulation — relevant for cardiovascular health.

How to Use

Take one packet (2 capsules) with breakfast and one packet with dinner. Taking LifePak with meals is important — the fat-soluble vitamins (A, D, E, K) and fat-soluble antioxidants (lutein, lycopene) require dietary fat for absorption. Splitting into two daily doses also improves absorption of water-soluble nutrients like B vitamins and vitamin C, which your body can only absorb in limited amounts at once.

If you're currently taking a basic multivitamin, you can switch directly — no transition period needed. If you're taking individual supplements (separate vitamin D, separate B-complex, separate antioxidant formula), check for overlap before stacking. LifePak's comprehensive formula means you likely won't need most of those standalone bottles anymore.

How It Compares

Comparison based on publicly available product information as of 2026. Features and formulations may change.

Who Is This For

Ideal for: Adults who want a single comprehensive supplement system instead of juggling 5-6 individual bottles. LifePak replaces your standalone multivitamin, antioxidant formula, and most mineral supplements in one package. Especially valuable if you've been using a budget multivitamin and want to step up to bioavailable forms without researching each nutrient individually.

Also suited for: Health-conscious Americans who've been curious about AG1 or other premium daily supplements but want full ingredient transparency. LifePak lists every ingredient and dose — no proprietary blends hiding behind "superfood complex" labels.

Not recommended for: Anyone looking for a single daily pill — LifePak requires two packets daily. Also not necessary if you already have a well-designed supplement stack with individually selected, high-quality nutrients in optimal forms. And if budget is the deciding factor, LifePak Elements (US$29.90) offers a streamlined version at a lower price point.

Frequently Asked Questions

Can I buy LifePak in the US without signing up?
Yes. No Nu Skin membership needed. NuBest Skin ships LifePak from the official US warehouse with no registration or auto-ship requirement.

What's the difference between LifePak and LifePak Nano?
LifePak Nano uses nanotechnology to further reduce particle size for improved absorption, particularly for the fat-soluble nutrients and CoQ10. It costs more (US$155.00) but delivers measurably higher blood levels of key nutrients. LifePak is the solid value choice; Nano is the absorption-optimized premium version. Both contain the same core nutrient profile.

I'm already taking AG1. Do I still need LifePak?
AG1 and LifePak serve different functions. AG1 is a greens powder with probiotics, adaptogens, and mushroom extracts — broad but at undisclosed doses. LifePak is a comprehensive multivitamin-mineral-antioxidant formula with full dose transparency. There's some overlap in basic vitamins, but LifePak's mineral coverage and antioxidant complex go well beyond what AG1 provides. You could use both, but if choosing one, the question is whether you value greens/adaptogens (AG1) or comprehensive micronutrients at transparent doses (LifePak).

What's the difference between this and what I can get at CVS for $15?
Primarily the nutrient forms and doses. Budget multivitamins use oxide-based minerals (4% absorption for magnesium oxide vs. 40-60% for chelated forms), synthetic vitamin E (one form instead of four), minimal antioxidant coverage, and RDA-level doses that prevent deficiency but don't optimize health. LifePak uses bioavailable forms, includes a full antioxidant complex, and doses at levels supported by clinical research. You absorb significantly more of what you're paying for.

Can I take LifePak alongside ageLOC R² or Y-Span?
Yes — they're designed to work together. LifePak covers foundational nutrition (vitamins, minerals, antioxidants). R² adds cellular energy and detoxification support. Y-Span targets gene expression for anti-aging. There's minimal ingredient overlap between the three. LifePak is the base layer; R² and Y-Span are targeted supplements that build on top of that foundation.

Works With

ageLOC R²: LifePak provides the nutritional foundation — the vitamins, minerals, and antioxidants your body needs daily. R² builds on that with targeted cellular energy (Day) and detoxification (Night) support. Think of LifePak as the base layer and R² as the performance upgrade. Together, they cover both foundational nutrition and cellular optimization.

Marine Omega: While LifePak includes some omega-3 coverage, Marine Omega provides a concentrated dose of EPA and DHA from krill and fish oil for cardiovascular and cognitive support. If heart health or brain function is a priority, adding Marine Omega gives you clinically meaningful omega-3 doses beyond what the multivitamin includes.

Beauty Focus Collagen+: LifePak's vitamin C and zinc support collagen synthesis, while Collagen+ provides the actual collagen peptides. They're complementary — LifePak ensures your body has the co-factors needed to use the collagen peptides effectively.

Important Information

FDA Notice: *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Consult your healthcare provider before use if you are pregnant, nursing, taking medication, or have a medical condition. Keep out of reach of children. Do not exceed the recommended daily intake.

Affiliate Disclosure: NuBest Skin is an Independent Nu Skin Brand Affiliate. This website is independently operated and is not produced, endorsed, supported, or affiliated with Nu Skin Enterprises, Inc. All product names, logos, and brands are property of their respective owners.

Sources & References

1. Schuette SA, et al. "Bioavailability of magnesium from common supplements." Journal of the American College of Nutrition, 2014. Comparative absorption of chelated vs. oxide mineral forms.
2. Jiang Q, et al. "Gamma-tocopherol and its metabolites in health and disease." American Journal of Clinical Nutrition, 2012. PMID: 22338079.
3. Feringa HH, et al. "The effect of grape seed extract on cardiovascular risk markers." Nutrition Reviews, 2020. PMID: 31504781.
4. National Institutes of Health (NIH) — Office of Dietary Supplements fact sheets on vitamin and mineral bioavailability.
5. Nu Skin Enterprises, Inc. — LifePak product documentation, Pharmanex research data.

Reviewed by the NuBest Skin Editorial Team. Last updated: April 2026.