Nano CoQ10 (Canada)

Every January through April, millions of Canadians layer up against indoor forced-air heating, commute in the dark, and quietly wonder why their energy levels feel like they've flatlined. For many — particularly those over 40, or anyone whose doctor has prescribed a statin — the culprit may be a cellular one: declining CoQ10. Pharmanex Nano CoQ10 delivers 30 mg of coenzyme Q10 in Nu Skin's proprietary CR-6 LipoNutrient nano-encapsulation system, designed to move past the absorption wall that makes standard CoQ10 supplements so unreliable. Blood level data show up to 5× higher plasma concentrations versus conventional crystalline CoQ10 — meaning a smaller labelled dose may out-perform a 100 mg standard capsule.

Best suited for: Canadians 40+ noticing declining energy; statin users whose natural CoQ10 synthesis is being suppressed; anyone already taking standard CoQ10 without noticeable benefit.

Less suited for: Those currently taking LifePak® Nano, which already includes 30 mg nano-encapsulated CoQ10 — adding this separately would be redundant unless directed by a healthcare practitioner.

Pairs well with: LifePak® Vitamin & Mineral Supplement, Nu Skin Marine Omega, ageLOC® R2 Night + Day

What Makes Nano CoQ10 Different

CoQ10 is fat-soluble — which sounds promising until you consider that the gut's absorption environment is primarily aqueous. Standard crystalline CoQ10 dissolves poorly and typically delivers as little as 2–3% of the labelled dose into the bloodstream. That is the core problem with most CoQ10 supplements on the shelf at Shoppers Drug Mart, whether from Jamieson, Webber Naturals, or Organika: the milligram count on the label tells you very little about how much actually reaches your mitochondria.

Nu Skin's CR-6 LipoNutrient technology takes a fundamentally different approach. CoQ10 molecules are wrapped inside food-grade lipid nanoparticles approximately 200 nm in diameter. This nano-encapsulation dramatically increases the surface area available for intestinal absorption and allows the lipid vehicle to bypass the aqueous solubility barrier almost entirely. Nu Skin's internal bioavailability studies showed absorption up to 5× higher than standard crystalline CoQ10 — meaning the 30 mg dose in Nano CoQ10 may deliver more usable CoQ10 to your cells than a 100–200 mg standard capsule.

The physiological stakes are real. CoQ10 is essential for mitochondrial ATP (energy) production. After age 40, natural biosynthesis declines by approximately 30%. For Canadians on HMG-CoA reductase inhibitors (statins) — a common prescription across Ontario, Alberta, and British Columbia — the depletion can be even steeper, since statins inhibit the same biochemical pathway that produces CoQ10 endogenously. This is not a fringe concern: Canadian Heart Association data indicate statin prescriptions are among the most common in the country, and CoQ10 depletion is a recognised consequence.

Key Ingredients

Ingredient	Amount	Role
CoQ10 (Ubiquinone) — nano-encapsulated	30 mg	Supports mitochondrial ATP production and cellular energy; delivered via CR-6 LipoNutrient system for enhanced bioavailability
Lipid Nanoparticle Vehicle	~200 nm particles	Food-grade lipid matrix that encapsulates CoQ10 molecules, bypassing aqueous solubility limitations of the gut

How to Use

Take 1 capsule daily with a meal containing fat. The lipid encapsulation already addresses the solubility barrier, but consuming alongside dietary fat provides additional absorption support. Morning or evening — timing is flexible. If you are on statin therapy, discuss CoQ10 supplementation with your healthcare practitioner before beginning.

How It Compares

Product	Dose	Delivery Form	Bioavailability Enhancement	Additional Notes
Pharmanex Nano CoQ10	30 mg	CR-6 LipoNutrient lipid nanoparticles (~200 nm)	Up to 5× vs. standard crystalline CoQ10 (internal study data)	Nano-encapsulation bypasses aqueous solubility barrier
Jamieson CoQ10 (Shoppers Drug Mart / Costco)	100–200 mg	Standard crystalline softgel	No specialised delivery; absorption dependent on co-ingested dietary fat	Higher label dose does not equate to proportionally higher plasma levels
Webber Naturals CoQ10 (Shoppers / Costco)	100–400 mg	Standard softgel or chewable	No nano-encapsulation; standard lipid carrier only	Crystalline CoQ10 bioavailability constrained by poor aqueous solubility
Organika CoQ10 (health food stores)	100 mg	Standard softgel with rice bran oil	Some improvement vs. dry crystalline capsule; no proprietary nanoparticle technology	Oil-based carrier improves dissolution modestly versus dry powder

Formulation comparison based on publicly available ingredient and delivery system information. No price comparison implied or intended.

Does Nano CoQ10 ship to my address in Canada?

Yes. Nano CoQ10 orders placed at nubestskin.com/ca ship from the official Nu Skin Canada warehouse. Standard delivery is typically 3–7 business days to most Canadian addresses, including Toronto, Vancouver, Calgary, Montreal, Ottawa, and Edmonton. Remote and Northern communities (Yukon, Northwest Territories, Nunavut) may experience longer transit times. No membership is required to order.

Is 30 mg actually enough — other brands offer 100–400 mg?

The labelled dose alone is not a reliable measure of therapeutic delivery. Standard crystalline CoQ10 at 100–200 mg delivers approximately 2–3% to the bloodstream. Due to CR-6 LipoNutrient nano-encapsulation, the 30 mg in Nano CoQ10 may reach plasma concentrations competitive with or exceeding much higher standard doses. The meaningful number is bioavailable CoQ10, not total milligrams on the label.

Should I take Nano CoQ10 if I'm on a statin?

Discuss with your healthcare practitioner before starting. Statins inhibit the mevalonate pathway, which is also the biosynthetic route for endogenous CoQ10. Canadian research and clinical guidance increasingly acknowledge that CoQ10 supplementation may be relevant for long-term statin users, though this should be assessed individually. A pharmacist at your local Shoppers Drug Mart can also advise on potential interactions with your current medication regimen.

How long before I may notice any change in energy levels?

Improved energy and reduced fatigue are typically reported at 4–6 weeks of consistent daily use. Plasma CoQ10 levels generally reach steady state at approximately 8–12 weeks. Results will vary by individual, baseline CoQ10 status, age, and whether any conditions are affecting CoQ10 synthesis or utilisation.

I already take LifePak® Nano — do I still need this?

No — not unless your healthcare practitioner advises a higher dose. LifePak® Nano already contains 30 mg nano-encapsulated CoQ10 via the same CR-6 LipoNutrient technology. Taking both simultaneously would mean doubling up on nano CoQ10 without a clinically established reason to do so. Nano CoQ10 as a standalone product is most relevant for those not already taking LifePak® Nano, or those who require a targeted, higher CoQ10 intake under practitioner guidance.

Does this require a Natural Product Number (NPN) to be sold in Canada?

Yes. Under Health Canada's Natural Health Products Regulations, all natural health products sold in Canada — including CoQ10 supplements — must carry a valid NPN (Natural Product Number) on the label, confirming that the product has been assessed for safety, efficacy, and quality. Pharmanex Nano CoQ10 is sold through official Nu Skin Canada channels and is regulated accordingly. If you need NPN information for your records, contact Nu Skin Canada directly.

Can I take Nano CoQ10 with blood thinners like warfarin?

This requires healthcare practitioner input. CoQ10 has structural similarity to vitamin K2, and there is some evidence in published literature of potential interaction with warfarin (affecting INR values). If you are on anticoagulant therapy, consult your physician or pharmacist before adding any CoQ10 supplement to your routine.

Works With

• LifePak® Vitamin & Mineral Supplement — CA$108.00 — comprehensive anti-ageing multivitamin foundation for those not yet on LifePak® Nano
• LifePak® Nano Anti-Aging Multivitamins — CA$189.00 — already includes 30 mg nano CoQ10; review overlap before combining
• Nu Skin Marine Omega — CA$69.00 — omega-3 fatty acids to support cardiovascular health alongside CoQ10
• ageLOC® R2 Night + Day — CA$148.00 — targets cellular energy and renewal pathways; complementary to mitochondrial CoQ10 support
• ageLOC® Meta — CA$136.00 — metabolic health formula that pairs well with cellular energy support
• CordyMax Cs-4® — CA$35.00 — adaptogenic energy support; commonly combined with CoQ10 for a comprehensive cellular energy approach

Sources & References

• Bhagavan, H. N., & Chopra, R. K. (2006). Coenzyme Q10: Absorption, tissue uptake, metabolism and pharmacokinetics. Free Radical Research, 40(5), 445–453. https://doi.org/10.1080/10715760600617843
• Crane, F. L. (2001). Biochemical functions of coenzyme Q10. Journal of the American College of Nutrition, 20(6), 591–598. https://doi.org/10.1080/07315724.2001.10719063
• Mortensen, S. A., et al. (2014). The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure. JACC: Heart Failure, 2(6), 641–649. https://doi.org/10.1016/j.jchf.2014.06.008
• Health Canada — Natural Health Products Regulations: https://www.canada.ca/en/health-canada/services/drugs-health-products/natural-non-prescription.html
• Nu Skin Enterprises. (2024). Nano CoQ10 — CR-6 LipoNutrient Bioavailability Data [internal product documentation].

Reviewed by the NuBest Skin Editorial Team. Last updated: June 2025.

*Independent Nu Skin Brand Affiliate — not produced or endorsed by Nu Skin Enterprises Inc.