ageLOC® TRME® SmartWin (Canada)

ageLOC TRMe SmartWin is the fat management component of Nu Skin's three-product TRMe weight management system. While RealMe handles appetite and MyTriumph supports metabolism, SmartWin targets how your body stores and processes dietary fat — specifically through CLA (conjugated linoleic acid), which has been the subject of over 30 clinical trials for its effects on body composition. SmartWin delivers 3,000 mg of CLA per daily dose alongside Nu Skin's ageLOC gene expression blend, targeting the fat metabolism gene clusters that become less efficient with age. For Canadians working to manage body composition through long, sedentary winters, SmartWin adds a fat-management layer to whatever dietary and exercise strategies you're already using.

What Makes ageLOC TRMe SmartWin Different

CLA supplements are available at every health food store in Canada. What makes SmartWin different isn't the CLA itself — it's the dose standardization, the ageLOC gene expression component, and the integration into the TRMe system.

Most commercial CLA products deliver 1,000–2,000 mg per day. SmartWin provides 3,000 mg — the dose range consistently associated with positive body composition outcomes in clinical research. A 2007 meta-analysis in the American Journal of Clinical Nutrition, analysing 18 trials, found that CLA at approximately 3.2 g per day produced a modest but consistent reduction in body fat mass compared to placebo, with effects most pronounced when maintained for 6+ months.

The ageLOC blend adds gene expression targeting for fat metabolism gene clusters — the genetic programs that regulate how efficiently your body mobilizes and oxidizes stored fat. As these programs downregulate with age, fat becomes increasingly stubborn to lose through diet and exercise alone.

Key Ingredients

CLA (Conjugated Linoleic Acid, 3,000 mg): A naturally occurring fatty acid found in meat and dairy. Research suggests CLA influences body composition through multiple mechanisms: inhibiting fat storage in adipocytes, promoting fat oxidation for energy, and supporting lean muscle mass retention during caloric restriction. The 2007 meta-analysis in the American Journal of Clinical Nutrition found an average fat loss of 0.09 kg per week with CLA supplementation.

ageLOC Proprietary Blend: Targets Youth Gene Clusters associated with fat metabolism. While CLA works through direct biochemical pathways, the ageLOC component addresses the gene expression changes that make fat metabolism less efficient with age.

How to Use

Take 3 softgels twice daily with meals (6 total per day). Taking with food containing some dietary fat improves CLA absorption, since it's a fat-soluble compound. Split between breakfast and dinner for consistent daily levels.

SmartWin works best when combined with regular physical activity. CLA's fat-oxidation effects are amplified by exercise — even moderate activity (30-minute walks, home workouts, swimming at your local YMCA or community centre) enhances the body composition benefits.

For Canadians, winter is when body fat tends to accumulate most. Starting SmartWin in October and maintaining through April covers the highest-risk period for fat gain. Pair with whatever indoor activity you can maintain — even mall walking counts when it's -30°C outside.

Results from CLA are gradual. Expect 6–12 weeks of consistent use before measurable body composition changes. This isn't a rapid fat-loss product — it's a sustained, evidence-based approach to fat management.

How It Compares

Feature	ageLOC TRMe SmartWin	Webber Naturals CLA 95	Jamieson CLA
CLA per Day	3,000 mg	3,000 mg (at 4 softgels)	1,500 mg (at 3 softgels)
Gene Expression Blend	Yes (ageLOC)	No	No
Part of Integrated System	Yes (TRMe trio)	Standalone	Standalone
Quality Process	6S (200+ tests)	GMP certified	GMP certified
Price	CA$95/month	~CA$30/month	~CA$20/month

Webber Naturals delivers the same CLA dose at a third of the price — if pure CLA is all you want, they're excellent value from a Canadian brand. SmartWin's premium buys the ageLOC gene expression component and the system integration with RealMe and MyTriumph. For standalone CLA supplementation, Webber Naturals or Jamieson work fine. For gene expression targeting and a three-product weight management system, SmartWin is the only option.

Who Is This For

If you're following a reasonable diet and exercise program but stubborn fat — particularly around the midsection — isn't responding the way it used to, age-related changes in fat metabolism gene expression may be a contributing factor. SmartWin targets that specific issue.

If you're using the full TRMe system, SmartWin is the third pillar: RealMe manages what goes in (appetite), MyTriumph manages how fast you burn it (metabolism), SmartWin manages how fat is stored and mobilized.

If you're a Canadian approaching or past 40 who's noticed that the same exercise routine produces fewer body composition results than it did a decade ago, the gene expression component addresses the age-related change that's reducing your returns.

Not suitable for anyone under 18, pregnant or nursing women, or individuals with liver conditions. CLA at therapeutic doses can occasionally cause GI discomfort in the first week — this typically resolves as your body adjusts.

Frequently Asked Questions

Q: How do I buy ageLOC TRMe SmartWin in Canada?

Order from nubestskin.com — no registration needed. Ships from the official Nu Skin Canada warehouse. Standard shipping: CA$2.99, free over CA$79. Delivery: 3–5 business days across Canada.

Q: Will CLA alone help me lose weight?

CLA isn't a weight-loss supplement in the traditional sense. Research shows it modestly shifts body composition — reducing fat mass while supporting lean mass — rather than causing rapid weight loss. Combined with reasonable diet and exercise, it improves the ratio of fat to muscle over time. Expect gradual, sustainable changes rather than dramatic drops on the scale.

Q: Can I just buy regular CLA instead of SmartWin?

You can — CLA supplements from Webber Naturals or Jamieson deliver the same base ingredient at lower cost. SmartWin's additional value is the ageLOC gene expression blend and integration into the TRMe system. If you're using RealMe and MyTriumph, SmartWin completes the system. If you want standalone CLA, budget options work fine.

Q: How long before I see body composition changes?

Clinical trials measured significant results at 8–12 weeks, with improvements continuing through 6 months of use. Body composition changes (more muscle definition, less midsection softness) appear before scale changes — your weight may not change much while your shape improves.

Q: Are there any side effects?

Some people experience mild digestive adjustment in the first week (slight nausea or loose stools). This typically resolves within 3–5 days. Taking softgels with meals reduces the likelihood of GI effects.

Works With

ageLOC TRMe RealMe: Manages appetite and cravings, reducing calorie intake. SmartWin then helps ensure that the calories you do consume are metabolized more efficiently rather than stored as fat.

ageLOC TRMe MyTriumph: Supports metabolic rate through thermogenesis. Combined with SmartWin's fat management, you get both increased calorie burn (MyTriumph) and improved fat utilization (SmartWin).

ageLOC TR90 Protein Boost: If you're actively exercising alongside TRMe, Protein Boost supports muscle recovery and lean mass development — which complements SmartWin's fat-to-muscle composition shift.

Important Information

Important Information: This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare practitioner before use, especially if you are pregnant, nursing, taking medication, or have a medical condition. This product has been assessed by Health Canada as a Natural Health Product. Individual results may vary. Store in a cool, dry place away from direct sunlight.

NuBest Skin is an Independent Nu Skin Brand Affiliate. This content is not produced or endorsed by Nu Skin Enterprises Inc.

Sources & References

Whigham, L. D., et al. (2007). Efficacy of conjugated linoleic acid for reducing fat mass: a meta-analysis in humans. American Journal of Clinical Nutrition, 85(5), 1203–1211.

Nu Skin Enterprises. (2024). ageLOC TRMe System — Fat Metabolism Gene Cluster Data.

Reviewed by the NuBest Skin Editorial Team. Last updated: April 2026.