ageLOC® Y-Span® (Australia)

ageLOC® Y-Span® — Nu Skin's Most Advanced Anti-Ageing Supplement

No one wants to look or feel old. Even as we age, most of us want our bodies and minds to keep feeling youthful, capable, and energetic. The challenge is giving your body what it actually needs to keep doing what it was designed to do — live young.

ageLOC® Y-Span® is Nu Skin's most advanced anti-ageing supplement ever developed. Built on more than three decades of scientific knowledge, it goes beyond general wellness support to target the actual sources of ageing — specifically, the gene expression patterns that govern how your body's ageing defence mechanisms perform over time. The result is a formula that doesn't just support healthy ageing, but actively promotes the optimal expression of key gene groups to help your body resist ageing at its source.*

What Is Youth Span — And Why Does It Matter?

ageLOC® Y-Span® is designed around a concept that extends beyond how long you live: your youth span — the years you can genuinely enjoy life being more active, energetic, and healthy. The goal isn't simply longevity. It's maintaining the vitality, clarity, and physical capacity to actually make the most of those years. That distinction shapes everything about how Y-Span was formulated and what it targets.*

Key Benefits

• ✔ Promotes your youth span — more active, energetic, healthy years*
• ✔ Supports healthy ageing defence mechanisms*
• ✔ Helps reduce free radical damage to body cells*
• ✔ Positively modulates gene expression to support healthy ageing*
• ✔ Promotes cellular health, brain health, heart health, bone health, eye health, immune health, and physical performance*
• ✔ Contains a unique blend of nutrients not readily available from even a healthy diet
• ✔ Level II Prysm Certified — guaranteed to improve your Skin Carotenoid Score as measured by Prysm iO

The Science: Gene Expression and Ageing Defence

Nu Skin has spent decades developing a unique understanding of how gene expression affects our ageing defence mechanisms. As we age, changes in how key genes are expressed cause our body's natural defences against ageing to decline in function and performance. ageLOC® Y-Span® directly addresses this — positively modulating gene expression across multiple ageing defence mechanisms simultaneously, rather than targeting only one pathway or symptom.*

This approach — targeting the sources of ageing rather than visible signs — is the foundation of the ageLOC® platform. Y-Span represents the most advanced expression of this philosophy, incorporating more than 30 years of accumulated scientific knowledge into a single, comprehensive daily supplement.*

Key Ingredients

• Omega-3 Triglycerides (Fish) — 527.5mg per serving, including EPA (150mg) and DHA (100mg) — essential fatty acids supporting brain, heart, and cellular health
• Vitamin D₃ (as cholecalciferol) — 6.25mcg (63% RDI) — supports bone, immune, and cellular health
• Vitamin K₂ (as menaquinone-7) — 10mcg — works synergistically with D₃ for bone structure
• Citrus Bioflavonoids Extract — 76.95mg — potent antioxidants supporting cardiovascular and cellular health
• R,S-Alpha-Lipoic Acid — 25mg — universal antioxidant supporting energy metabolism and free radical defence
• Quercetin — 18.75mg — plant flavonoid with antioxidant and anti-inflammatory properties
• Ubidecarenone (CoQ₁₀) — 7.5mg — supports cellular energy production and heart health
• Rosemary Leaf Extract (Rosmarinus officinalis) — 9.375mg — antioxidant supporting cellular protection
• Lutein — 1mg — carotenoid supporting eye health and protection
• Lycopene — 1.25mg — antioxidant carotenoid supporting cardiovascular and cellular health
• Astaxanthin — 0.25mg — one of the most potent natural antioxidants, supporting skin and cellular protection
• Japanese Knotweed Root Extract (Reynoutria japonica) — 1.2g — natural source of resveratrol, supporting longevity pathways
• Purple Corn Flower Stalk Extract (Zea mays) — 1.133g — rich in anthocyanins supporting antioxidant defence
• Orange Oil (Citrus sinensis) — 13.16mg

Other Ingredients: Gelatin, Glycerin, Yellow Beeswax, Water, Sunflower Oil, Maltodextrin, Lecithin (Sunflower), Olive Oil, Vanillin, Mixed Tocopherols, Medium Chain Triglycerides, dl-Alpha Tocopherol.

Contains: Fish, Sulphites.

How ageLOC® Y-Span® Compares to Other Anti-Ageing Supplements in Australia

Australia's health supplement market includes a wide range of products making anti-ageing and wellness claims. Here's how ageLOC Y-Span compares to some of the most recognised options available to Australian consumers:

Feature	ageLOC® Y-Span®	Blackmores Bio C + Antioxidants	Swisse Ultiboost Healthy Ageing	Bioceuticals OmegaForte	Nutra-Life CoQ10 150mg
Core Approach	Gene expression modulation targeting ageing at source	Vitamin C + general antioxidants	Traditional herbs + vitamins	Omega-3 EPA/DHA focused	Single CoQ10 ingredient
Proprietary Research	30+ years Nu Skin-exclusive R&D	Ingredient-level studies	Traditional use evidence	Published omega-3 research	CoQ10 ingredient studies
Gene Expression Targeting	✔ Multiple ageing defence pathways*	✗ Not targeted	✗ Not targeted	✗ Not targeted	✗ Not targeted
Brain Health Support	✔ DHA + multiple actives*	✗ Not targeted	Partial via herbs	✔ DHA focused	✗ Not targeted
Heart Health Support	✔ Omega-3 + CoQ10 + Lycopene*	Partial via antioxidants	Partial via herbs	✔ EPA/DHA focused	✔ CoQ10 focused
Eye Health Support	✔ Lutein + Astaxanthin*	✗ Not targeted	✗ Not targeted	✗ Not targeted	✗ Not targeted
Bone Health Support	✔ Vitamin D₃ + K₂*	✗ Not targeted	Partial (varies by formula)	✗ Not targeted	✗ Not targeted
Measurable Skin Score	✔ Level II Prysm Certified	No equivalent	No equivalent	No equivalent	No equivalent
Ingredient Breadth	13+ actives across multiple systems	3-4 actives	5-8 herbal actives	1-2 actives (omega-3)	Single active

Most anti-ageing supplements available in Australian pharmacies and health stores take a single-pathway approach — omega-3 for heart and brain, CoQ10 for energy, antioxidants for free radical defence. ageLOC® Y-Span® addresses all of these simultaneously, while additionally targeting the gene expression patterns that govern how ageing defence mechanisms perform at a fundamental level — something no single-ingredient or general wellness formula can replicate.*

How to Use

Take two softgels twice daily — once with your morning meal and once with your evening meal. Consistent twice-daily dosing maintains steady levels of active nutrients across the full 24-hour cycle, aligned with the body's natural biological rhythms.*

Keep out of reach of children. Pregnant or breastfeeding women, and people with known medical conditions, should consult a healthcare practitioner before use. Discontinue use and consult a healthcare practitioner if any adverse reactions occur. Do not use if safety seal is broken or missing.

Contains fish and sulphites — not suitable for those with fish or sulphite allergies or sensitivities.

Frequently Asked Questions

What is a Prysm Certified product?
Prysm Certification means Nu Skin's scientists are confident this product will raise your skin carotenoid score as measured by the Prysm iO scanner. Carotenoids are an important class of antioxidants found in fruits, vegetables, and supplements. If a product is Prysm Certified, you can expect consistent use to increase your scanner score over time.*

Will ageLOC Y-Span raise my Skin Carotenoid Score?
Yes — ageLOC Y-Span is Level II Prysm Certified, meaning it will raise your scanner score when taken as directed. This is a guaranteed outcome backed by Nu Skin's scientific confidence in the formula.*

What do different Prysm Certification levels mean?
A higher Prysm Certification level means you can expect a greater increase in your scanner score compared to a product with a lower level. This is based on the quantity and bioavailability of carotenoids in each product. A Level II Prysm Certified product like Y-Span will produce larger score increases than a Level I product.*

What are ageing defence mechanisms?
Ageing defence mechanisms are your body's natural systems for fighting off and maintaining resistance to the effects of ageing. As we get older, changes in gene expression cause these mechanisms to decline in function and performance. ageLOC Y-Span supports and maintains the activity of these mechanisms — helping your body continue functioning more youthfully.*

Why can't I get these nutrients from diet alone?
Y-Span contains a unique blend of nutrients — including concentrated plant extracts standardised for specific active compounds — that would be difficult or impossible to obtain at effective levels from food alone, even a well-balanced diet. The formula delivers consistent, efficacious levels of these nutrients twice daily, which diet simply cannot replicate reliably.*

Who should take ageLOC Y-Span?
ageLOC Y-Span is formulated for adults who want to proactively support their body's natural ageing defence mechanisms. It's particularly relevant for those in their 30s, 40s, 50s and beyond — when declining gene expression begins to measurably affect how the body's defence systems perform. Always read the label. If you are pregnant, breastfeeding, or managing a known medical condition, consult your healthcare practitioner before use.

Can I take ageLOC Y-Span with other supplements?
For most healthy adults, Y-Span is compatible with standard supplement routines. However, because it contains omega-3 fatty acids, vitamin K₂, and concentrated plant extracts at efficacious levels, it's advisable to check with your GP or pharmacist if you are taking prescription medications — particularly blood thinners or anticoagulants — before adding Y-Span to your routine.

How long before I notice results?
ageLOC Y-Span works at a cellular and gene expression level — changes are real but gradual. Most users find that consistent use over 8–12 weeks, taken twice daily as directed, is where cumulative benefits become most noticeable. Energy levels and general vitality may show earlier improvement, while structural benefits — bone, joint, eye health — develop over longer periods of consistent use.*

Why twice daily instead of once?
The twice-daily dosing is deliberate — morning and evening with meals maintains more consistent blood levels of the active nutrients across the full 24-hour cycle. A single daily dose would produce peak-and-trough fluctuations that reduce the sustained benefit the formula is designed to deliver.*

How does ageLOC Y-Span differ from ageLOC Meta?
These two products target different aspects of health and work well together. ageLOC Meta focuses specifically on metabolic health — supporting the biochemical processes related to blood sugar, inflammation, gut health, and vital organs — powered by an exclusive anthocyanin blend. ageLOC Y-Span takes a broader anti-ageing approach, targeting gene expression and multiple ageing defence mechanisms across cellular, brain, heart, bone, eye, immune health, and physical performance — through a comprehensive 13+ ingredient formula. Many users take both as complementary daily supplements.*

Is ageLOC Y-Span suitable for vegetarians or vegans?
No — Y-Span contains fish-derived omega-3 triglycerides (from anchovies, sardines, and mackerel) and gelatin capsules. It is not suitable for vegetarians, vegans, or those with fish or sulphite allergies.

Authoritative References

• National Institute on Aging — Biology of Aging: Research Today
• National Health and Medical Research Council (NHMRC) — Australian Dietary Guidelines
• López-Otín et al. — The Hallmarks of Aging. Cell (landmark review)
• Heart Foundation Australia — Omega-3 and Heart Health
• Traber & Stevens (2011) — Vitamins C and E: Beneficial effects from a mechanistic perspective. Free Radical Biology and Medicine

*Always read the label and follow the directions for use.