Estera® Phase III Women's Maintenance Formula (USA)

Estera® Phase III — Postmenopausal Wellness for the Long Run

Once menopause is complete, the acute symptoms usually subside — but the health implications of permanently lower estrogen are just beginning. Estrogen plays protective roles in bone density, cardiovascular function, cognitive health, and metabolic regulation. When it declines permanently, these systems lose a key protective factor. Estera® Phase III is the Maintenance Formula — designed for long-term postmenopausal support, helping your body sustain bone, heart, brain, and metabolic health in estrogen's absence.

This isn't about replacing estrogen. It's about providing the nutritional support that helps your body compensate for estrogen's reduced protective effects. Phase III delivers phytoestrogen compounds that provide gentle, plant-based estrogen receptor activity, DIM for ongoing healthy estrogen metabolite ratios, and bone-supporting nutrients at levels reflecting postmenopausal requirements.

Key Benefits

• Ongoing Estrogen Metabolite Support — DIM continues to support favorable estrogen metabolite ratios even postmenopause, when low-level estrogen production from the adrenal glands and fat tissue still produces metabolites that benefit from proper liver processing
• Bone Density Maintenance — Delivers calcium, vitamin D3, and supporting nutrients at levels reflecting the increased requirements of postmenopausal women, who can lose up to 20% of bone density in the 5-7 years following menopause
• Cardiovascular Support — B vitamins for homocysteine management and other heart-supportive nutrients help compensate for the cardiovascular protection that estrogen previously provided
• Cognitive Function — Nutrients that support brain health and cognitive clarity, addressing the cognitive changes some women experience after menopause
• Healthy Lipid Profile — Supports maintenance of healthy cholesterol levels, which tend to shift unfavorably after menopause as estrogen's lipid-regulating effects diminish

Key Ingredients

Phase III's formulation shifts from Phase II's symptom-relief focus to long-term maintenance — emphasizing bone, cardiovascular, and cognitive support alongside continued estrogen metabolism optimization.

• DIM (Diindolylmethane) — Continues supporting healthy estrogen metabolism through liver pathways. Even postmenopause, your body produces small amounts of estrogen from adrenal glands and adipose tissue. DIM helps ensure these residual estrogens are metabolized through beneficial pathways
• Calcium + Vitamin D3 (Enhanced Dose) — Postmenopausal women need higher calcium and vitamin D intake than premenopausal women. The National Osteoporosis Foundation recommends 1,200mg calcium and 800-1,000 IU vitamin D3 daily for postmenopausal women. Phase III is formulated with these evidence-based requirements in mind
• Phytoestrogen Complex — Plant-based compounds providing gentle estrogen receptor interaction, helping maintain the cellular signaling that estrogen previously supported in bone, cardiovascular, and brain tissue
• B-Vitamin Complex — B6, B12, and folate support healthy homocysteine levels, which tend to rise postmenopause and are an independent risk factor for cardiovascular disease

How Nu Skin's Approach Differs

Most postmenopausal supplements are either bone-focused (calcium + D3, period) or general women's multivitamins without specific postmenopausal targeting. Estera Phase III addresses the full spectrum of postmenopausal health needs — bone, cardiovascular, cognitive, and metabolic — while maintaining estrogen metabolism support through DIM. The Phase II/III distinction ensures you're getting a formula optimized for your current hormonal status, not a one-size-fits-all approach.

Manufactured under the 6S Quality Process with standardized botanical extracts and verified mineral content. Calcium source quality is particularly important — Phase III uses chelated forms for optimal absorption.

How It Compares

Comparison based on publicly available product information as of 2025. Features and formulations may change.

How to Use

Take the recommended daily dose with food. Phase III is designed for ongoing daily use throughout your postmenopausal years — this isn't a short-term supplement. Split the dose between meals for optimal calcium absorption. Pair with weight-bearing exercise for maximum bone health benefit.

Who Should Consider This Product

Estera Phase III is for women who have completed menopause (12+ consecutive months without a period) and want comprehensive nutritional support for the long-term health changes that lower estrogen creates. It's particularly relevant if you have risk factors for osteoporosis, cardiovascular disease, or cognitive decline. If you're still in active perimenopause with symptoms, Phase II is more appropriate. Discuss with your doctor if you have hormone-sensitive conditions or are on HRT.

Frequently Asked Questions

Q: When should I switch from Phase II to Phase III?

A: Once your perimenopausal symptoms have largely resolved and you've gone 12+ consecutive months without a period (the clinical definition of menopause). Your healthcare provider can confirm your menopausal status if you're unsure.

Q: Can I take this with LifePak?

A: Yes, but be mindful of total calcium and vitamin D intake between the two products. Calculate your combined daily intake to avoid exceeding the upper limit of 2,000-2,500mg calcium and 4,000 IU vitamin D per day.

Q: How long should I take Phase III?

A: Phase III is designed for long-term use throughout your postmenopausal years. The bone, cardiovascular, and metabolic support needs it addresses are ongoing — they don't resolve with short-term supplementation.

Q: Is this safe to take with blood pressure medication?

A: Phase III ingredients are generally well-tolerated alongside common medications. However, as with any supplement, inform your healthcare provider about what you're taking, particularly if you're on blood thinners, thyroid medication, or cardiovascular drugs.

Q: Will the phytoestrogens cause issues if I had hormone-sensitive cancer?

A: This is an important question that requires your oncologist's input. Phytoestrogens interact with estrogen receptors at much lower potency than endogenous estrogen, but any estrogen-receptor interaction should be discussed with your cancer care team before starting.

Shipping & Payment

Payment Methods: Credit Card, Apple Pay, Google Pay, PayPal, PayPal Pay Later

Shipping: US-wide delivery, typically 3-7 business days

Shipping Cost: US$2.99 flat rate

Free Shipping: On orders over US$79

References

• NIH Office of Dietary Supplements — Calcium Fact Sheet
• NIH Office of Dietary Supplements — Vitamin D Fact Sheet
• PubMed — DIM Modulates Estrogen Metabolism (Nutrition and Cancer, 2004)
• Nu Skin Official — Estera Phase III Product Page

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

NuBest Skin is an independent Nu Skin Brand Affiliate. This product listing is not produced or endorsed by Nu Skin Enterprises, Inc.