ageLOC® Youth (Y-Span) Anti-aging Supplement (US)

ageLOC® Youth — Nu Skin's Most Advanced Anti-Aging Supplement

Every cell in your body comes equipped with natural defenses — biological mechanisms designed to resist the effects of aging. When you're young, these systems work efficiently. But over time, a combination of internal changes and external stressors — UV exposure, oxidative stress, poor sleep, environmental toxins, and simply the passage of time — begins to weaken these defenses. The result is what most of us experience as "getting older": declining energy, reduced mental sharpness, weaker joints, slower recovery.

ageLOC® Youth was built to address this at the source. Not by masking symptoms, but by providing your body with the specific nutrients it needs to maintain and revitalize the aging defense mechanisms that keep you feeling and functioning younger. Built on more than a decade of Nu Skin's proprietary anti-aging research, it represents the most advanced supplement in the ageLOC lineup — and one of the most comprehensively studied anti-aging formulas available today.*

The Concept of Youth Span

ageLOC Youth is designed around a concept that goes beyond lifespan: youth span — the years you can genuinely enjoy life feeling active, energetic, and healthy. The goal isn't simply to live longer, but to spend more of those years feeling your best. That distinction drives everything about how this formula was developed and what it targets.*

What ageLOC Youth Supports

• ✔ Promotes youthfulness and supports the body's natural aging defense mechanisms*

• ✔ Supports DNA damage protection and repair*

• ✔ Supports healthy brain structure and function*

• ✔ Supports normal blood glucose control and healthy glucose metabolism*

• ✔ Supports bone structure and integrity*

• ✔ Promotes healthy joint fluidity*

• ✔ Supports healthy eye composition and protection*

• ✔ Promotes healthy immune function and response*

The Science: What Makes This Formula Different

The ageLOC Youth Blend is not a collection of standard vitamins or minerals you could replicate with a trip to the drugstore. It's a proprietary combination of potent nutrients and concentrated plant extracts — standardized for active compounds — that would be difficult, if not impossible, to obtain at effective levels through diet alone, even a well-balanced one.

As we age, changes in gene expression cause our aging defense mechanisms to decline in function and performance. ageLOC Youth specifically targets these mechanisms — supporting the biological pathways that keep cells functioning more youthfully. This is the core of the ageLOC philosophy: target the sources of aging, not just the visible signs.*

The formula delivers efficacious levels of these nutrients twice daily — morning and evening — aligned with the body's natural biological rhythms for optimal uptake and sustained benefit throughout the day and night.*

Clinically Studied Ingredients

ageLOC Youth is backed by multiple published clinical studies — both on the individual ingredients and on the formula itself:

• A 2020 study published in Free Radical Biology and Medicine found that supplementation with a calorie restriction mimetic micronutrient blend — a key component of the ageLOC Youth formula — increased glutathione concentrations and improved neuroenergetics in the brains of healthy middle-aged men and women.*

• A 2016 study published in the Journal of Cosmetic Dermatology documented protective effects of the nutritional and phytonutrient blend on UV-induced skin damage and inflammatory response through aging defense mechanisms.*

This level of published, peer-reviewed clinical evidence on a complete supplement formula — not just individual ingredients — is rare in the supplement industry.

Prysm Certified

ageLOC Youth is Prysm Certified — meaning Nu Skin's scientists have confirmed it will raise your skin carotenoid score as measured by the Prysm iO™ scanner. This certification reflects the quantity and bioavailability of carotenoids in the formula, providing an objective, measurable indicator of the supplement's nutritional impact on your body.*

Key Ingredients

• ageLOC Youth Blend — A proprietary combination of powerful anti-aging nutrients and concentrated phytonutrient extracts, standardized for active compounds and clinically verified to support healthy aging defense mechanisms

• Other Ingredients: Gelatin, Glycerin, Beeswax, Sunflower Lecithin, Vanillin

• Contains Fish: Anchovies, sardines, mackerel

How ageLOC® Youth Compares to Other Anti-Aging Supplements

The anti-aging supplement market in the US is large and often overcrowded with products making broad claims with limited clinical backing. Here's how ageLOC Youth compares to some of the most recognized anti-aging supplements available to American consumers:

Most anti-aging supplements on the US market focus on a single pathway — NAD+ precursors, resveratrol, or broad-spectrum vitamins. ageLOC Youth takes a fundamentally different approach: targeting multiple aging defense mechanisms simultaneously across eight distinct areas of health, backed by formula-level clinical studies rather than ingredient-level assumptions alone.*

How to Use

Adults over 18: take two softgels twice daily — once with your morning meal and once with your evening meal. Consistent twice-daily dosing maintains steady levels of active nutrients throughout the day and night.*

Keep out of reach of children. Pregnant or lactating women, and people with known medical conditions, should consult a physician prior to use. Discontinue use and consult a physician if any adverse reactions occur. Do not use if safety seal is broken or missing. Contains fish (anchovies, sardines, mackerel) — not suitable for those with fish allergies.

Sustainability

Nu Skin has eliminated the outer carton historically included with ageLOC Youth — reducing packaging waste without compromising product integrity. Please recycle remaining packaging according to your local capabilities.

Frequently Asked Questions

What are aging defense mechanisms?
Aging defense mechanisms are your body's way of fighting off and maintaining resistance to aging aggressors. As we age, changes in gene expression cause the body's aging defense mechanisms to decline in function, performance, and ability. ageLOC Youth maintains and supports the activity of aging defense mechanisms, helping you live more youthfully.*

Can't I get these nutrients from a healthy diet?
ageLOC Youth contains a unique ingredient blend that provides broad-spectrum benefits for everyone, regardless of dietary intake or supplement regimen. ageLOC Youth provides a potent blend of anti-aging ingredients, including concentrated extracts standardized for active compounds that would be difficult, if not impossible, to obtain at the same levels and on a regular basis — even from a healthy, well-balanced diet. Furthermore, ageLOC Youth delivers efficacious levels of these powerful nutrients and phytochemicals at consistent levels twice per day.*

Is ageLOC Youth Prysm Certified?
Yes — ageLOC Youth is Prysm Certified, meaning Nu Skin's scientists are confident this product will raise your skin carotenoid score (Prysm score) as measured by Prysm iO™. Prysm Certification reflects the quantity and bioavailability of carotenoids in the product. A higher Prysm certification level indicates a greater expected increase in your score over time.*

What happened to the outer carton?
As responsible stewards of our planet, Nu Skin has proudly eliminated the carton historically included with ageLOC Youth. Please check your local capabilities and recycle the remaining packaging where possible. By purchasing ageLOC Youth, you're joining us in taking an active stride to ensure the future is bright for both the planet and each of us.*

Who should take ageLOC Youth?
ageLOC Youth is formulated for adults over 18 who want to proactively support their body's natural aging defense mechanisms. It's particularly relevant for those in their 30s, 40s, 50s and beyond — when declining gene expression begins to measurably affect how the body's defense systems perform. If you are pregnant, breastfeeding, or managing a known medical condition, consult your physician before use.

Can I take ageLOC Youth with other supplements or medications?
For most healthy adults, ageLOC Youth is compatible with standard supplement routines. However, because the formula contains concentrated phytonutrient extracts at efficacious levels, it's always advisable to check with your physician or pharmacist if you are taking prescription medications — particularly blood thinners, diabetes medications, or immunosuppressants — before adding any new supplement.

How long before I notice results?
ageLOC Youth works at a cellular and biochemical level — changes are real but gradual. Most users find that consistent use over 8–12 weeks, taken twice daily as directed, is where cumulative benefits become most noticeable. Some areas — such as energy levels and general vitality — may show earlier improvement, while structural benefits (bone, joint, eye health) develop over longer periods of consistent use.*

Why twice daily instead of once?
The twice-daily dosing — morning and evening with meals — is deliberate. It maintains more consistent blood levels of the active nutrients throughout the full 24-hour cycle, aligning with the body's natural biological rhythms. A single daily dose would result in peak-and-trough fluctuations that reduce the sustained benefit the formula is designed to deliver.*

Does ageLOC Youth contain allergens?
Yes — ageLOC Youth contains fish (anchovies, sardines, mackerel). It is not suitable for individuals with fish or seafood allergies. The softgel capsule also contains gelatin, making it unsuitable for vegans and vegetarians who avoid animal-derived ingredients.

How does ageLOC Youth differ from ageLOC Meta?
These two products target different aspects of health and work well together. ageLOC Meta focuses specifically on metabolic health — supporting the biochemical processes related to blood sugar, inflammation, gut health, and vital organs — powered by an exclusive anthocyanin blend. ageLOC Youth takes a broader approach, targeting eight distinct aging defense mechanisms across the body — from DNA repair and brain function to bone, joint, eye, and immune health — through a comprehensive proprietary nutrient blend. Many users take both as complementary daily supplements.*

Authoritative References

• Mastaloudis et al. (2020) — Calorie restriction mimetic micronutrient blend, glutathione, and neuroenergetics in healthy middle-aged adults. Free Radical Biology and Medicine

• Wood et al. (2016) — Nutritional and phytonutrient blend protective effects on UV-induced skin damage. Journal of Cosmetic Dermatology

• National Institute on Aging — Biology of Aging: Research Today

• Harvard T.H. Chan School of Public Health — Antioxidants and Aging Defense

• López-Otín et al. — The Hallmarks of Aging. Cell (landmark review)

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.