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ageLOC Tru Face Peptide Retinol Complex is Nu Skin's answer to the retinol dilemma: you want the proven anti-ageing benefits of retinoids (reduced fine lines, improved texture, more even tone), but you don't want the redness, peeling, and sensitivity that traditional retinol often brings. This formula pairs two gentle-yet-effective retinoid compounds with an AI-discovered peptide to deliver visible improvement in fine lines, wrinkles, hyperpigmentation, and pore appearance — with initial results reported from day seven in Nu Skin's clinical testing.
Traditional retinol (retinyl palmitate, retinaldehyde, or prescription tretinoin) works by accelerating cell turnover. It's effective, but the side effects are well-documented: redness, flaking, increased sun sensitivity, and an initial "purging" period where skin often looks worse before it improves. Many people in the UK try retinol in autumn, experience the irritation, and abandon it before seeing benefits.
The Peptide Retinol Complex uses two retinoid compounds at concentrations chosen specifically to deliver results without triggering the irritation cascade. Combined with the AI-discovered peptide — identified through Nu Skin's machine learning analysis of thousands of potential actives — the formula achieves comparable outcomes through a gentler mechanism. No mandatory adjustment period, no purging phase, no need to avoid the (admittedly limited) UK sunshine.
Dual retinoid complex: Two complementary retinoid compounds working at different depths within the skin to improve texture, tone, and fine line appearance.
AI-discovered peptide: Identified through computational analysis of peptide libraries, this active targets multiple visible signs of ageing simultaneously — fine lines, uneven tone, and loss of firmness.
ageLOC blend: Targets gene expression clusters associated with skin ageing at the cellular level.
Barrier-supporting complex: Maintains skin barrier integrity during the retinoid treatment, reducing the likelihood of sensitivity or dryness.
Apply one to two pumps to clean skin each evening. Start with every-other-night application for the first week if you have particularly sensitive skin, though most people tolerate nightly use from the outset. Follow with your moisturiser — the Transforming Gel Cream for lighter coverage, or the Uplifting Rich Cream if your skin tends toward dryness.
Use sunscreen the following morning. While this formula is gentler than traditional retinol, retinoids still increase skin's sensitivity to UV exposure, and that applies year-round — not just in summer.
Week one: smoother skin texture, slight improvement in radiance. Weeks two to four: visible reduction in fine lines, pores appear smaller, tone begins to even out. Weeks four to eight: more significant improvement in deeper lines, hyperpigmentation fading, overall skin quality noticeably improved. The peptide and retinoid components have complementary timelines — the peptide delivers faster surface results while the retinoids build deeper structural improvements over time.
Individual results may vary. This product is intended for cosmetic use only and is not designed to diagnose, treat, cure, or prevent any disease or skin condition. Discontinue use if irritation occurs and consult a dermatologist or your GP. Patch test recommended before first use.
Clinical results referenced are from studies conducted or commissioned by Nu Skin Enterprises, Inc. and may not reflect typical consumer experience.
NuBest Skin is an Independent Nu Skin Brand Affiliate. This website is independently operated and is not produced, endorsed, or approved by Nu Skin Enterprises, Inc.
Product information reviewed by the NuBest Skin Editorial Team. Last updated April 2026.
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