Nu Skin FlexCare® (Singapore)

Nu Skin FlexCare combines glucosamine, chondroitin, and MSM (methylsulfonylmethane) in a single joint health supplement designed to support cartilage maintenance, joint flexibility, and comfortable movement. Each daily dose provides 1,500 mg glucosamine, 1,200 mg chondroitin sulphate, and 900 mg MSM — dosages aligned with those used in the major published clinical studies on joint health supplementation.

What Makes FlexCare Different

Many joint supplements provide only one or two of the three key joint-support compounds, or use sub-clinical doses. FlexCare delivers all three — glucosamine, chondroitin, and MSM — at the full doses used in published research. The landmark GAIT (Glucosamine/chondroitin Arthritis Intervention Trial) study, published in the New England Journal of Medicine in 2006 with 1,583 participants, used 1,500 mg glucosamine and 1,200 mg chondroitin — the same doses in FlexCare. The addition of 900 mg MSM provides organic sulphur, a building block for connective tissue that supports the glucosamine-chondroitin combination.

Singapore’s fitness culture has expanded significantly — participation in running events increased by over 30% between 2018 and 2024, and gym membership rates are among the highest in Southeast Asia. Running on hard surfaces along East Coast Park, MacRitchie Reservoir, or city pavements places repetitive impact stress on knee and ankle joints. For older Singaporeans, daily stair climbing in HDB blocks (where approximately 80% of the resident population lives) and walking distances within MRT stations add up. FlexCare addresses joint comfort and flexibility for both active fitness enthusiasts and the growing active-ageing population navigating Singapore’s built environment.

Key Ingredients

Glucosamine HCl (1,500 mg daily dose): Glucosamine is a naturally occurring amino sugar that serves as a building block for glycosaminoglycans, key structural components of cartilage. Supplemental glucosamine supports the body’s ability to maintain and repair cartilage tissue. The 1,500 mg daily dose matches the dosage used in the GAIT study and the European GUIDE trial, both of which assessed glucosamine supplementation over 6-month and 3-year periods respectively.

Chondroitin Sulphate (1,200 mg daily dose): A naturally occurring component of cartilage that helps retain water within the cartilage matrix, supporting its shock-absorbing capacity. Chondroitin also supports the inhibition of enzymes that break down cartilage. The 1,200 mg dose reflects the clinical study standard.

MSM — Methylsulfonylmethane (900 mg daily dose): An organic sulphur compound found naturally in some fruits, vegetables, and grains. Sulphur is a critical element in collagen and keratin production. MSM supports joint comfort and flexibility, and a 2006 pilot study published in Osteoarthritis and Cartilage found that 3,000 mg MSM twice daily improved joint function scores over 12 weeks.

How to Use

Take the recommended daily dose in divided portions with meals — typically split between breakfast and dinner for steady absorption. Each bottle contains a 30-day supply. Joint health supplements work cumulatively, so consistent daily use for 8–12 weeks is recommended before evaluating results. Many published studies assessed outcomes at the 3-month and 6-month marks. For runners and gym-goers, taking a dose before or after training does not provide immediate joint relief — the benefit comes from consistent long-term cartilage support rather than acute effects. Store in a cool, dry place away from Singapore’s ambient heat and humidity.

Frequently Asked Questions

How is FlexCare shipped in Singapore?
Orders ship from the official Nu Skin Singapore warehouse. Standard shipping is S$4.99, or free on orders over S$99. Delivery takes 1–3 business days to most Singapore addresses.

How long does FlexCare take to work?
Joint health supplements like FlexCare are not fast-acting pain relievers. Clinical studies on glucosamine and chondroitin typically assess outcomes after 8–12 weeks of consistent use, with the GAIT study evaluating at the 24-week mark. Most users report noticeable improvements in joint comfort and flexibility after 2–3 months of daily use.

Is FlexCare suitable for runners?
Absolutely. Running — particularly on hard surfaces like Singapore’s pavements and park connectors — creates repetitive impact on knee, ankle, and hip joints. The glucosamine and chondroitin in FlexCare support cartilage maintenance, which is directly relevant for regular runners. Many distance runners use joint-support supplements as a proactive measure alongside proper footwear and training volume management.

Can I take FlexCare if I have a shellfish allergy?
Glucosamine is commonly derived from shellfish. Check the product label for the specific glucosamine source used in FlexCare. If you have a confirmed shellfish allergy, consult your healthcare professional before taking any glucosamine-containing supplement.

Can I combine FlexCare with other Nu Skin supplements?
FlexCare pairs well with other supplements. Users commonly combine it with Marine Omega (for anti-inflammatory omega-3 support) or LifePak (for comprehensive daily nutrition). There are no known interactions between FlexCare’s ingredients and standard multivitamin or omega-3 formulations.

Important Information

Important Information: This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare professional before use, especially if you are pregnant, nursing, taking medication, or have a medical condition. Health supplements are regulated by the Health Sciences Authority (HSA) of Singapore. Individual results may vary. Store in a cool, dry place away from direct sunlight — this is especially important in Singapore’s tropical climate.

NuBest Skin is an Independent Nu Skin Brand Affiliate. This content is not produced or endorsed by Nu Skin Enterprises Inc.

Sources & References

Product information sourced from official Nu Skin product documentation. GAIT study referenced from Clegg et al., New England Journal of Medicine, 2006 (1,583 participants). MSM pilot study referenced from Kim et al., Osteoarthritis and Cartilage, 2006. Singapore HDB residency data sourced from Housing & Development Board annual report. Singapore running participation data referenced from Sport Singapore and event registration statistics, 2018–2024.

Reviewed by the NuBest Skin Editorial Team. Last updated: April 2026.