Estera® Phase III Women's Maintenance Formula (U.S)

Product Overview

Estera® Phase III Women's Maintenance Formula is a daily dietary supplement formulated to support hormonal balance across multiple life stages. Designed for women in both childbearing and post-menopausal years, it addresses three primary concerns: moderating estrogen metabolite ratios, relieving common post-menopausal symptoms such as hot flashes and night sweats, and supporting long-term bone and cardiovascular health. The formula combines standardized phytoestrogen extracts, liver-supportive compounds, and antioxidant botanicals into a single capsule serving. Ships from official Nu Skin warehouse through local NuBest stores worldwide.

Key Ingredients & Science

• Soy Bean Extract (Glycine max, 300:1) — 90 mg: Standardized to 18 mg isoflavone glucosides (genistin and daidzin). Isoflavones act as selective estrogen receptor modulators (SERMs), binding weakly to estrogen receptors and helping modulate estrogenic activity. Meta-analyses support their role in reducing hot flash frequency and maintaining bone mineral density.
• Flaxseed Extract (Linum usitatissimum, 8:1) — 75 mg: Standardized to 15 mg secoisolariciresinol diglucoside (SDG). SDG is a lignan precursor converted by gut microbiota into enterolactone and enterodiol — phytoestrogens associated with a healthier estrogen metabolite ratio and antioxidant activity.
• Pomegranate Extract (Punica granatum, 55:1) — 20 mg: Equivalent to 1.1 g fresh fruit. Rich in ellagitannins, pomegranate demonstrates antioxidant and mild estrogenic activity supporting hormonal comfort during perimenopause and post-menopause.
• Indole-3-Carbinol (I3C): A phytochemical derived from cruciferous vegetables. I3C promotes conversion of estrogen toward the less potent 2-hydroxyestrone metabolite, supporting a favorable estrogen metabolite ratio and liver detoxification pathways.

How to Use

Take one capsule daily with food, or as directed by a healthcare professional. Estera® Phase III is designed as a daily maintenance supplement and is best incorporated into an established morning or evening routine. Consistency over multiple weeks is recommended to assess full benefit. Do not exceed the stated serving size unless advised by a qualified health practitioner.

Frequently Asked Questions

What is Estera® Phase III Women's Maintenance Formula?

Estera® Phase III is a once-daily dietary supplement formulated to support hormonal balance, liver metabolism of estrogen, and relief from post-menopausal symptoms including hot flashes, night sweats, decreased libido, and reduced cognitive sharpness. It is designed for women in both childbearing and post-menopausal life stages.

What are the key active ingredients in Estera® Phase III?

The primary actives are a standardized soy isoflavone extract (genistin and daidzin), flaxseed lignan extract (secoisolariciresinol diglucoside), pomegranate extract, and Indole-3-Carbinol (I3C). Each ingredient contributes distinct mechanisms targeting estrogen receptor modulation, metabolite clearance, and antioxidant defense.

How does Estera® Phase III work?

The formula works through multiple pathways: phytoestrogens (isoflavones and lignans) bind weakly to estrogen receptors to moderate hormonal signaling; I3C and lignans support liver-mediated conversion of estrogen toward less potent metabolites; and pomegranate extract provides antioxidant protection. Together, these mechanisms address both the symptomatic and longer-term health aspects of hormonal change.

How does Estera® Phase III fit into a supplement routine?

It functions as a standalone daily hormonal maintenance supplement. It can be taken alongside a broad-spectrum multivitamin or bone-support formula but should not be combined with other concentrated phytoestrogen or estrogen-modulating supplements without professional guidance. Taking with food improves tolerability.

What results can I expect and in what timeframe?

Botanical phytoestrogen supplements typically require four to twelve weeks of consistent daily use before noticeable changes in symptom frequency or intensity are observed. Individual response varies depending on baseline hormone levels, gut microbiome composition (which affects lignan conversion), and overall dietary phytoestrogen intake.

Available Worldwide

This product is available through NuBest Skin in 37 countries worldwide. Visit your local NuBest store for pricing, availability, and country-specific product information.

NuBest Skin is an Independent Nu Skin Brand Affiliate. This website is independently operated and is not produced, endorsed, or approved by Nu Skin Enterprises, Inc.

This product is a dietary supplement and is not intended to diagnose, treat, cure, or prevent any disease. Regulations vary by country — check your local NuBest store for country-specific compliance information.