ageLOC® R² Night + Day

Product Overview

ageLOC® R² Night + Day is a two-part nutritional supplement system developed by Nu Skin under its ageLOC® platform — a science program focused on addressing the sources of ageing rather than surface-level symptoms. The system pairs a daytime formula with a nighttime formula, working across two biological windows to support three core dimensions of vitality that commonly decline with age: physical vigour, mental acuity, and sexual health. The kit is designed to raise and sustain baseline energy levels, support cellular detoxification processes, and help protect cells from damage caused by external toxins. Ships from official Nu Skin warehouse through local NuBest stores worldwide.

Key Ingredients & Science

ageLOC® R² Night + Day is formulated around the ageLOC® platform's focus on Youth Gene Clusters (YGCs) — gene expression patterns associated with youthful cellular function. The dual-formula approach targets two complementary biological mechanisms:

• Day Formula: Designed to optimise cellular energy production by supporting mitochondrial function. Key actives work to enhance the body's natural ATP synthesis pathways, improving sustained energy without stimulant dependency.
• Night Formula: Focused on cellular purification during the body's natural overnight repair cycle. Ingredients support autophagy — the process by which cells neutralise and remove damaged proteins and toxic byproducts — helping to restore cellular integrity.

Together, the formulas are intended to support the body's own protective mechanisms against oxidative stress and cellular waste accumulation — processes directly linked to biological ageing. In a consumer study, 90% of users reported positive changes in fatigue levels while taking the product, or noticed increased fatigue after discontinuing use.

How to Use

Take six (6) ageLOC® R² Day capsules each morning. Take two (2) ageLOC® R² Night capsules each evening. Use consistently as part of a daily wellness routine. Do not take while on warfarin therapy without medical advice. Pregnant or lactating women and individuals with known medical conditions should consult a physician prior to use.

Frequently Asked Questions

What is ageLOC® R² Night + Day?

ageLOC® R² Night + Day is a dual-formula dietary supplement system from Nu Skin's ageLOC® line. It uses a Day formula and a Night formula taken at separate times to support cellular energy production and cellular detoxification across a full 24-hour cycle.

What are the key active ingredients in ageLOC® R² Night + Day?

The system contains proprietary ageLOC® ingredient blends targeting mitochondrial energy support in the Day formula and cellular purification and autophagy support in the Night formula. Full ingredient details are available on the product label and through your local NuBest store.

How does ageLOC® R² Night + Day work?

The Day formula supports mitochondrial function to promote sustained physical and mental energy. The Night formula supports the body's natural overnight cellular cleansing processes, helping neutralise and remove cellular waste and toxic byproducts accumulated during daily activity.

How does ageLOC® R² Night + Day fit into a supplement routine?

It functions as a foundational daily supplement system. The Day capsules are taken with your morning routine, while the Night capsules align with the body's natural repair cycle during sleep. It can be used alongside other ageLOC® products as part of a broader wellness regimen.

What results can I expect and in what timeframe?

Users commonly report improved energy levels and reduced fatigue with consistent daily use. Individual results vary based on lifestyle, health status, and adherence. Consumer research indicates that changes in fatigue perception may be noticeable during ongoing use, with effects also reported upon discontinuation.

Is ageLOC® R² Night + Day suitable for everyone?

It is not recommended for pregnant or lactating women without prior physician consultation. Individuals with known medical conditions or those on warfarin therapy should seek medical advice before use. Keep out of reach of children. Consult your healthcare provider if any adverse reactions occur.

Available Worldwide

This product is available through NuBest Skin in 37 countries worldwide. Visit your local NuBest store for pricing, availability, and country-specific product information.

NuBest Skin is an Independent Nu Skin Brand Affiliate. This website is independently operated and is not produced, endorsed, or approved by Nu Skin Enterprises, Inc.

This product is a dietary supplement and is not intended to diagnose, treat, cure, or prevent any disease. Regulations vary by country — check your local NuBest store for country-specific compliance information.