ageLOC® Y-Span® (Canada)

ageLOC Y-Span — Nu Skin's Most Advanced Anti-Ageing Supplement, Built for Canadian Lifestyles

Canadians spend up to five months of every year in conditions that actively work against their health — reduced daylight hours drive Vitamin D levels dangerously low, harsh winters limit outdoor activity, and seasonal dietary shifts mean fewer fresh nutrients when your body needs them most. ageLOC Y-Span was formulated to address exactly this kind of compounding deficit. Rather than offering a single vitamin or isolated antioxidant, it delivers a comprehensive blend of 13+ scientifically selected ingredients that work together to target gene expression patterns governing your body's own ageing defence mechanisms. The goal isn't just longevity — it's extending your "youth span," the years you spend feeling energetic, sharp, and physically capable.

Backed by over 30 years of Nu Skin's anti-ageing research and Level II Prysm Certified to improve your Skin Carotenoid Score, Y-Span represents a fundamentally different approach to supplementation: instead of reacting to symptoms, it targets the underlying genetic processes that determine how well your body ages.

Why This Matters for Canadians Specifically

Health Canada data consistently shows that a significant proportion of Canadians are deficient in Vitamin D, particularly during the October-to-April stretch when UVB exposure drops below effective levels across most provinces. Y-Span includes Vitamin D3 alongside Vitamin K2 — a pairing that emerging research suggests works synergistically for both bone density and cardiovascular health. Add in the Omega-3 fatty acids (EPA 150mg + DHA 100mg per serving) that support brain function and heart health during sedentary winter months, and you have a supplement that's genuinely aligned with the Canadian health landscape — not just a repackaged formula designed for sunnier climates.

Key Benefits

• ✔ Cellular Health — Targets gene expression patterns associated with ageing, supporting your body's natural defence and renewal processes at a foundational level.
• ✔ Brain Health — Omega-3 fatty acids (DHA) and Alpha-Lipoic Acid support cognitive function, focus, and mental clarity — especially relevant during dark Canadian winters when mood and energy dip.
• ✔ Heart Health — EPA, CoQ10, and Quercetin contribute to cardiovascular function, helping maintain healthy circulation through cold-weather months.
• ✔ Bone Health — Vitamin D3 paired with Vitamin K2 supports calcium metabolism and bone mineral density — critical for Canadians who get limited sun exposure for up to half the year.
• ✔ Eye Health — Lutein, Lycopene, and Astaxanthin provide targeted antioxidant support for your eyes against blue light exposure and oxidative stress.
• ✔ Immune Support — A broad-spectrum antioxidant profile including Vitamin D3, Quercetin, and Citrus Bioflavonoids strengthens your immune response when seasonal illness peaks.
• ✔ Physical Performance — CoQ10 supports cellular energy production, while the overall formula helps maintain stamina and recovery capacity as you age.
• ✔ Level II Prysm Certified — Independently verified to improve your Skin Carotenoid Score, a biomarker of overall antioxidant status.

The Science — How Gene Expression Targeting Works

Traditional supplements deliver nutrients and hope for the best. ageLOC Y-Span takes a different approach entirely. Nu Skin's research identified specific gene expression clusters — called Youth Gene Clusters — that govern the biological processes behind ageing. As these clusters become less active over time, the visible and internal signs of ageing accelerate: slower recovery, reduced energy, declining cognitive sharpness, weakened immunity.

Y-Span's formulation is designed to influence these gene expression patterns, essentially supporting the body's own mechanisms for staying young rather than just patching individual deficiencies. The 13+ active ingredients were selected not just for their individual benefits, but for how they interact as a system — each component amplifying the effectiveness of the others.

Key Ingredients & Amounts (Per 4 Softgels Daily)

• Omega-3 Fatty Acids — EPA 150mg + DHA 100mg: support brain, heart, and joint health.
• Vitamin D3 — essential for bone health, immune function, and mood regulation; particularly important for Canadians with limited winter sun exposure.
• Vitamin K2 — works synergistically with D3 to direct calcium into bones rather than arteries.
• Coenzyme Q10 (CoQ10) — supports cellular energy production and cardiovascular health; natural levels decline with age.
• Alpha-Lipoic Acid — a versatile antioxidant that functions in both water- and fat-soluble environments, supporting cellular defence.
• Quercetin — a plant flavonoid with antioxidant and anti-inflammatory properties that supports immune and cardiovascular health.
• Citrus Bioflavonoids — enhance antioxidant activity and support healthy circulation.
• Rosemary Extract — provides additional antioxidant protection and supports cognitive function.
• Lutein — a carotenoid that filters blue light and supports macular health.
• Lycopene — a potent antioxidant supporting cellular health and skin protection.
• Astaxanthin — one of nature's most powerful antioxidants, supporting eye health, skin resilience, and physical recovery.
• Japanese Knotweed Root Extract (Resveratrol) — supports cardiovascular health and cellular longevity pathways.
• Purple Corn Extract (Anthocyanins) — delivers concentrated polyphenols with strong antioxidant and anti-inflammatory properties.

Full Ingredient List

Fish Oil (Omega-3: EPA, DHA), Gelatin (softgel capsule), Glycerin, Purified Water, Beeswax, Lecithin (Soy), Vitamin D3 (Cholecalciferol), Vitamin K2 (Menaquinone-7), Coenzyme Q10, Alpha-Lipoic Acid, Quercetin Dihydrate, Citrus Bioflavonoids, Rosemary Leaf Extract, Lutein (from Marigold Flower Extract), Lycopene, Astaxanthin, Japanese Knotweed Root Extract (Polygonum cuspidatum, standardised for Resveratrol), Purple Corn Extract (Zea mays L.), Silicon Dioxide, Mixed Tocopherols (antioxidant). Contains: Fish, Soy, Sulphites. Not suitable for vegetarians or vegans.

How ageLOC Y-Span Compares to Popular Canadian Supplements

The difference is fundamental. Products like Jamieson and Webber Naturals address individual nutritional gaps effectively — and they're solid choices for that purpose. But Y-Span isn't designed to fill gaps. It's engineered as an integrated system that targets the genetic mechanisms behind ageing itself. AOR Ortho Core comes closest in ingredient breadth, but lacks the gene expression targeting, Astaxanthin, and Prysm certification that distinguish Y-Span.

How to Use

Take 2 softgels twice daily — morning and evening, with meals. The twice-daily dosing maintains steady nutrient levels across the full 24-hour cycle, ensuring consistent support for your body's renewal processes. Each pack contains 120 softgels (a 30-day supply).

Storage: Keep in a cool, dry place below 30°C. Keep out of reach of children. Precautions: Contains fish and sulphites — not suitable for vegetarians or vegans. If you are pregnant, nursing, taking medication, or have a medical condition, consult your healthcare practitioner before use.

Frequently Asked Questions

How is Y-Span different from a standard multivitamin?
A multivitamin fills nutritional gaps. Y-Span does something fundamentally different — it targets the gene expression patterns that govern how your body ages. The 13+ ingredients were selected not just for their individual benefits, but for how they work together as a system to support your body's own ageing defence mechanisms. Think of it less as a supplement and more as a precision intervention.

Why is the Vitamin D3 + K2 combination important for Canadians?
Most Canadians are Vitamin D deficient from October through April due to insufficient UVB exposure. D3 supplementation helps — but without K2, the calcium that D3 helps absorb can deposit in arteries rather than bones. The D3 + K2 pairing in Y-Span ensures calcium goes where it's needed, supporting both bone density and cardiovascular health through the long Canadian winter.

How long before I notice results?
Most users report noticeable improvements in energy, mental clarity, and overall vitality within 8–12 weeks of consistent use. Some notice subtle changes earlier — particularly in energy levels and sleep quality. The gene expression benefits compound over time, so continued use delivers the most significant results.

Can I take Y-Span alongside LifePak or other Nu Skin supplements?
Y-Span is designed to complement the Nu Skin supplement ecosystem. It pairs particularly well with ageLOC R² for enhanced cellular energy. If you're already taking LifePak, consult your healthcare practitioner to review total nutrient intake and avoid doubling up on specific vitamins.

Is Y-Span suitable for younger adults, or is it only for older people?
Ageing begins at the cellular level well before it shows externally. Y-Span is appropriate for adults who want to proactively support their body's ageing defence mechanisms — typically from the mid-30s onward, though younger adults with specific health goals may benefit as well. Consult your healthcare practitioner if you're under 30.

Why take it twice daily instead of once?
The twice-daily dosing (morning and evening with meals) maintains consistent nutrient levels throughout the full 24-hour cycle. Many of Y-Span's active ingredients have relatively short half-lives in the body, so splitting the dose ensures your cells have continuous access to the compounds they need for optimal gene expression support.

What does "Level II Prysm Certified" mean?
Prysm certification is an independent verification that a product demonstrably improves your Skin Carotenoid Score — a non-invasive biomarker that reflects your body's overall antioxidant status. Level II certification means the improvement has been validated to a higher standard, giving you objective evidence that the supplement is working.

Are there any allergens I should be aware of?
Y-Span contains fish oil and sulphites. It also contains soy-derived lecithin. It is not suitable for vegetarians or vegans. If you have allergies to any of these ingredients, or if you're taking blood-thinning medication (Omega-3 and Vitamin K2 can interact), consult your healthcare practitioner before starting.

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*Always read the label and follow the directions for use.